protein

Recombinant Human CD34 GST Tag

MBS142848

0.002 mg

265 USD

Recombinant Protein

Recombinant Human CD34 GST Tag

CD34

CD34 Human, GST; CD34 Human Recombinant, GST Tag; Hematopoietic progenitor cell antigen CD34; CD34; CD34 GST

hematopoietic progenitor cell antigen CD34 isoform a; Hematopoietic progenitor cell antigen CD34; hematopoietic progenitor cell antigen CD34; CD34 antigen; CD34 molecule; CD_antigen: CD34

CD34

CD34; CD34

CD34_HUMAN

E Coli

385

CD34 in 50mM Tris-HCl, pH7.5, 10mM L-glutathione (reduced). Sterile Filtered clear solution.

Store vial at -20 degree C to -80 degree C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.

RECOMBINANT & NATURAL PROTEINS; CD Antigens

Description: CD34 Human Recombinant full length expressed in E Coli, CD34 is antibody reactive.The CD34 is purified by proprietary chromatographic techniques. Introduction: CD34 is a single chain transmembrane glycoprotein which is selectively expressed on human lymphoid and myeloid hemapoietic progenitor cells.CD34 has been used to measure angiogenesis, which reportedly predicts tumor recurrence.

68342038

NP_001020280.1

NM_001025109.1

P28906

35,011 Da

Adaptive Immune System Pathway (366160); C-MYB Transcription Factor Network Pathway (138073); Cell Adhesion Molecules (CAMs) Pathway (83069); Cell Adhesion Molecules (CAMs) Pathway (480); Hematopoietic Cell Lineage Pathway (83078); Hematopoietic Cell Lineage Pathway (489); Immune System Pathway (106386); Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway (106413)

The protein encoded by this gene may play a role in the attachment of stem cells to the bone marrow extracellular matrix or to stromal cells. This single-pass membrane protein is highly glycosylated and phosphorylated by protein kinase C. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

CD34: Possible adhesion molecule with a role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. Could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. Presents carbohydrate ligands to selectins. Selectively expressed on hematopoietic progenitor cells and the small vessel endothelium of a variety of tissues. Belongs to the CD34 family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Cell surface; Membrane protein, integral. Chromosomal Location of Human Ortholog: 1q32. Cellular Component: intercellular bridge; perinuclear region of cytoplasm; lysosome; integral to plasma membrane; cytoplasm; apical plasma membrane; basal plasma membrane; plasma membrane; external side of plasma membrane. Molecular Function: sulfate binding; carbohydrate binding; transcription factor binding. Biological Process: positive regulation of odontogenesis; cell proliferation; positive regulation of angiogenesis; cell-cell adhesion; regulation of immune response; negative regulation of nitric oxide biosynthetic process; endothelial cell proliferation; regulation of blood pressure; glomerular filtration; cell motility involved in cell locomotion; tissue homeostasis; negative regulation of blood coagulation; hemopoiesis; negative regulation of tumor necrosis factor production; signal transduction; leukocyte migration; positive regulation of interleukin-10 production

0.002 mg

265 USD

0.005 mg

365

0.01 mg

610