catalog number :
MBS142841
products type :
Native Protein
products full name :
Bovine Aprotinin
products short name :
Aprotinin
products name syn :
Aprotinin; Aprotinin; Pancreatic trypsin inhibitor; Basic protease inhibitor; BPI; BPTI; Aprotinin; AP; bAprotinin
other names :
Pancreatic trypsin inhibitor; Pancreatic trypsin inhibitor; Aprotinin; Basic protease inhibitor; BPI; BPTI
other gene names :
BPI; BPTI
uniprot entry name :
BPT1_BOVIN
purity :
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein (1mg/ml) was lyophilized with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Aprotinin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Aprotinin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info1 :
Unit Defenition: 1 Unit corresponds to 1 biological kallikrein inhibitor unit (KIU)1 TIU =1,300 KIU.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Aprotinin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Activity: 6,246 KIU (Kallikrein Inactivator Units) per mg, 3.47 TIU/mg.
products categories :
RECOMBINANT & NATURAL PROTEINS; Natural Proteins; Aprotinin
products description :
Description: Aprotinin is a natural proteinase inhibitor polypeptide consisting of fifty-eight amino acids {C 284 H 432 N 84 O 79 S 7} arranged in a single polypeptide chain, cross-linked by three disulfide bridges and having a molecular mass of 6512. Introduction: Aprotinin inhibits the activity of several proteolytic enzymes such as chymotrypsin, kallikrein, plasmin and trypsin. Aprotinin is present in blood and in most tissues, with a high concentration in lung. Aprotinin inhibits pro-inflammatory cytokine release and maintains glycoprotein homeostasis. In platelets, aprotinin reduces glycoprotein loss (e.g., GpIb, GpIIb/IIIa), while in granulocytes it prevents the expression of pro-inflammatory adhesive glycoproteins (e.g., CD11b).
ncbi mol weight :
10,903 Da