catalog number :
MBS142818
products type :
Recombinant Protein
products full name :
Recombinant Human cyclin-dependent kinase 16
products short name :
cyclin-dependent kinase 16
products name syn :
CDK16 Human; cyclin-dependent kinase 16 Human Recombinant; Cyclin-Dependent Kinase 16; PCTK1; Serine/Threonine-Protein Kinase; Serine/Threonine-Protein Kinase PCTAIRE-1; Cell Division Protein Kinase 16; PCTAIRE Protein Kinase 1; PCTAIRE; PCTGAIRE; EC 2.7.11.22; EC 2.7.11; PCTAIRE-Motif Protein Kinase 1; PCTAIRE1
other names :
PMF1-BGLAP protein isoform 2; HCG2044777; PMF1-BGLAP protein; polyamine-modulated factor 1; PMF1-BGLAP readthrough; HCG2044777
products gene name :
CDK16
other gene names :
PMF1-BGLAP; PMF1-BGLAP; PMF1
uniprot entry name :
U3KQ54_HUMAN
purity :
Greater than 95% as determined by SDS-PAGE.
form :
CDK16 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 0.1M NaCl and 10% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
products categories :
PROTEIN KINASES; Enzymes; Protein Kinases
products description :
Description: CDK16 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 362 amino acids (158-496aa) and having a molecular mass of 41.1kDa.CDK16 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: CDK16 is a member of the CDK family of serine/threonine protein kinases which are known to regulate the cell cycle. These proteins have a core kinase domain flanked by unique amino- and carboxy- terminal domains. CDK16, which is expressed mainly in mammalian brain, cooperates with an assortment of proteins, and is a part of a multiple signal transduction cascade.
ncbi acc num :
NP_001186591.1
ncbi gb acc num :
NM_001199662.1
ncbi mol weight :
23,769 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); M Phase Pathway (105812); Mitotic Anaphase Pathway (105818); Mitotic Metaphase And Anaphase Pathway (730317); Mitotic Prometaphase Pathway (105815); Resolution Of Sister Chromatid Cohesion Pathway (730315); Separation Of Sister Chromatids Pathway (730318)
ncbi summary :
This locus represents naturally occurring read-through transcription between the neighboring PMF1 (polyamine-modulated factor 1) and BGLAP (bone gamma-carboxyglutamate Gla protein) genes on chromosome 1. Alternative splicing results in multiple transcript variants encoding isoforms that share sequence identity with the upstream gene product, but they contain distinct C-termini due to frameshifts versus the downstream gene coding sequence. [provided by RefSeq, Dec 2010]