catalog number :
MBS142799
products type :
Recombinant Protein
products full name :
Recombinant Human Protein Kinase, AMP-Activated, Gamma 1
products short name :
[Kinase]
products name syn :
[PRKAG1 Human; Protein Kinase, AMP-Activated, Gamma 1 Human Recombinant; Protein Kinase AMP-Activated Gamma 1 Non-Catalytic Subunit; 5'-AMP-Activated Protein Kinase Subunit Gamma-1; AMPK Gamma1 Chain; AMPKg]
other names :
[5'-AMP-activated protein kinase subunit gamma-1 isoform 3; 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase subunit gamma-1; 5'-AMP-activated protein kinase, gamma-1 subunit; AMPK gamma-1 chain; AMPK gamma1; protein kinase, AMP-activated, gamma 1 non-catalytic subunit]
products gene name :
[PRKAG1]
other gene names :
[PRKAG1; PRKAG1; AMPKG; AMPK gamma1; AMPK subunit gamma-1; AMPKg]
uniprot entry name :
AAKG1_HUMAN
sequence :
MGSSHHHHHH SSGLVPRGSH MGS METVISS DSSPAVENEH PQETPESNNS VYTSFMKSHR CYDLIPTSSK LVVFDTSLQV KKAFFALVTN GVRAAPLWDS KKQSFVGMLT ITDFINILHR YYKSALVQIY ELEEHKIETW REVYLQDSFK PLVCISPNAS LFDAVSSLIR NKIHRLPVID PESGNTLYIL THKRILKFLK LFITEFPKPE FMSKSLEELQ IGTYANIAMV RTTTPVYVAL GIFVQHRVSA LPVVDEKGRV VDIYSKFDVI NLAAEKTYNN LDVSVTKALQ HRSHYFEGVL KCYLHETLET IINRLVEAEV HRLVVVDEND VVKGIVSLSD ILQALVLTGG EKKP
purity :
Greater than 85.0% as determined by SDS-PAGE.
form :
The PRKAG1 solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. Sterile Filtered clear solution.
products categories :
PROTEIN KINASES; Enzymes; Protein Kinases
products description :
Description: PRKAG1 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 354 amino acids (1-331) and having a molecular mass of 40.0kDa.PRKAG1 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: PRKAG1 is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer comprised of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is a vital energy-sensing enzyme which supervises cellular energy status. PRKAG1 is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding dissimilar isoforms were found.
ncbi acc num :
NP_001193638.1
ncbi gb acc num :
NM_001206709.1
ncbi mol weight :
38,533 Da
ncbi pathways :
AMPK Signaling Pathway (198868); AMPK Signaling Pathway (989139); AMPK Signaling Pathway (992181); Activation Of PPARGC1A (PGC-1alpha) By Phosphorylation Pathway (1127496); Adipocytokine Signaling Pathway (83093); Adipocytokine Signaling Pathway (505); Circadian Rhythm Pathway (83084); Circadian Rhythm Pathway (495); Energy Metabolism Pathway (198907); Energy Dependent Regulation Of MTOR By LKB1-AMPK Pathway (160972)