product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Phosphoserine Phosphatase
catalog :
MBS142770
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142770
products type :
Recombinant Protein
products full name :
Recombinant Human Phosphoserine Phosphatase
products short name :
Phosphoserine Phosphatase
products name syn :
PSPH Human; Phosphoserine Phosphatase Human Recombinant; Phosphoserine phosphatase; EC 3.1.3.3; PSP; O-phosphoserine phosphohydrolase; PSPase; L-3-phosphoserine phosphatase; PSPH
other names :
phosphoserine phosphatase; Phosphoserine phosphatase; phosphoserine phosphatase; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase; PSPase; phosphoserine phosphatase; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase
products gene name :
PSPH
other gene names :
PSPH; PSPH; PSP; PSPHD; PSP; PSPase
uniprot entry name :
SERB_HUMAN
host :
E Coli
sequence length :
225
sequence :
MVSHSELRKL FYSADAVCFD VDSTVIREEG IDELAKICGV EDAVSEMTRR AMGGAVPFKA ALTERLALIQ PSREQVQRLI AEQPPHLTPG IRELVSRLQE RNVQVFLISG GFRSIVEHVA SKLNIPATNV FANRLKFYFN GEYAGFDETQ PTAESGGKGK VIKLLKEKFH FKKIIMIGDG ATDMEACPPA DAFIGFGGNV IRQQVKDNAK WYITDFVELL GELEE.
purity :
Greater than 95.0% as determined by(a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
form :
The protein contains 20mM Hepes pH 7.5, 1mM DTT &100mM KCl2. Sterile filtered colorless solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.
products categories :
PROTEIN KINASES; Enzymes; Phosphatase
products description :
Description: Phosphoserine Phosphatase Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 225 amino acids and having a molecular mass of 25 kDa. PSP was overexpressed in E Coli and purified by conventional chromatography. Introduction: Human Phosphoserine phosphatase (hPSP) is an important enzyme in the phosphorylated pathway of serine biosynthesis, which contributes a major portion of the endogenous L-serine. Similar to known L-3-phosphoserine phosphatases, it catalyzed the Mg2+-dependent hydrolysis of L-phosphoserine and an exchange reaction between L-serine and L-phosphoserine. Recently, its complex structures reveal that the open-closed environmental change of the active site, generated -helical bundle domain, is important to substrate by local rearrangement of the recognition and hydrolysis.
ncbi gi num :
46249388
ncbi acc num :
NP_004568.2
ncbi gb acc num :
NM_004577.3
uniprot acc num :
P78330
ncbi mol weight :
25,008 Da
ncbi pathways :
Amino Acid Synthesis And Interconversion (transamination) Pathway 106173!!Biosynthesis Of Amino Acids Pathway 790012!!Biosynthesis Of Amino Acids Pathway 795174!!Carbon Metabolism Pathway 814926!!Carbon Metabolism Pathway 817567!!Glycine, Serine And Threonine Metabolism Pathway 82949!!Glycine, Serine And Threonine Metabolism Pathway 313!!Metabolic Pathways 132956!!Metabolism Pathway 477135!!Metabolism Of Amino Acids And Derivatives Pathway 106169
ncbi summary :
The protein encoded by this gene belongs to a subfamily of the phosphotransferases. This encoded enzyme is responsible for the third and last step in L-serine formation. It catalyzes magnesium-dependent hydrolysis of L-phosphoserine and is also involved in an exchange reaction between L-serine and L-phosphoserine. Deficiency of this protein is thought to be linked to Williams syndrome. [provided by RefSeq, Jul 2008]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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