catalog number :
MBS142654
products type :
Native Protein
products full name :
Human Leuprolide
products short name :
Leuprolide
products name syn :
Leuprorelin Human; Leuprolide Human; Leuprolide; Leuprorelin; Leuprorelin
sequence :
pGlu-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt.
purity :
Greater than 98.0% as determined by RP-HPLC.
form :
The Leuprorelin was lyophilized from a concentrated (1 mg/ml) solution with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Leoprolide although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Leuprorelin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Leoprolide in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
products categories :
HORMONES; Hormones; Peptide Hormones
products description :
Description: Leuprolide Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1209 Dalton. The molecular formula is C59H84N16O12. Introduction: Leuprorelin (INN) or leuprolide acetate (USAN) is a gonadotropin-releasing hormone agonist (GnRH agonist).By causing constant stimulation of the pituitaryGnRH receptors, it initially causes stimulation (flare), but thereafter decreases pituitary secretion (downregulation) of gonadotropins luteinizing hormone(LH) and follicle-stimulating hormone(FSH).Like other GnRH agonists, leuprolide may be used in the treatment of hormone-responsive cancers such as prostate canceror breast cancer, estrogen-dependent conditions (such as endometriosisor uterine fibroids), to treat precocious puberty, and to control ovarian stimulation in IVF.