Human Oxytocin | MyBioSource MBS142648 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Human Oxytocin

catalog :

MBS142648

quantity :

5 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS142648

products type :

Native Protein

products full name :

Human Oxytocin

products short name :

Oxytocin

products name syn :

OT Human; Oxytocin Human; OT; OXT; OT-NPI; Neurophysin 1; MGC126890; MGC126892

other names :

oxytocin-neurophysin 1 preproprotein; Oxytocin-neurophysin 1; oxytocin-neurophysin 1; neurophysin I; oxytocin, prepro- (neurophysin I); oxytocin, prepropeptide; oxytocin-neurophysin I, preproprotein; oxytocin/neurophysin I prepropeptide; Ocytocin

products gene name :

other gene names :

OXT; OXT; OT; OT-NPI; OXT-NPI; OT; OT-NPI

uniprot entry name :

NEU1_HUMAN

sequence length :

125

sequence :

Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2.

purity :

Greater than 99.0% as determined by RP-HPLC.

form :

The Oxytocin was lyophilized from a concentrated (1 mg/ml) solution with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.

storage stability :

Lyophilized Oxytocin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Neurophysin 1 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

other info1 :

Specific Activity: 1mg of Oxytocin has activity greater than 480IU.

other info2 :

Solubility: It is recommended to reconstitute the lyophilized Oxytocin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

products categories :

HORMONES; Hormones

products description :

Description: Oxytocin Human Synthetic is a single, non-glycosylated, polypeptide chain containing 9 amino acids and having a molecular mass of 1007.2 Dalton. Oxytocin has a molecular formula of C43H66N12O12S2. The OT is purified by proprietary chromatographic techniques. Introduction: Human Oxytocin stimulates uterine smooth muscle contractions indirectly and stimulates the mammary glands to increase lactation without increasing the production of milk.

ncbi gi num :

4505537

ncbi acc num :

NP_000906.1

ncbi gb acc num :

NM_000915.3

uniprot acc num :

P01178

ncbi mol weight :

12,722 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Myometrial Relaxation And Contraction Pathways (198759); Oxytocin Signaling Pathway (952859)

ncbi summary :

This gene encodes a precursor protein that is processed to produce oxytocin and neurophysin I. Oxytocin is a posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. [provided by RefSeq, Dec 2013]

uniprot summary :

OXT: Neurophysin 1 specifically binds oxytocin. Belongs to the vasopressin/oxytocin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 20p13. Cellular Component: extracellular space; extracellular region; terminal button; secretory granule. Molecular Function: oxytocin receptor binding; neurohypophyseal hormone activity. Biological Process: response to peptide hormone stimulus; response to cAMP; male mating behavior; heart development; drinking behavior; response to glucocorticoid stimulus; positive regulation of female receptivity; female pregnancy; signal transduction; positive regulation of synaptic transmission; response to estradiol stimulus; elevation of cytosolic calcium ion concentration; hyperosmotic salinity response; negative regulation of blood pressure; response to electrical stimulus; response to food; grooming behavior; response to retinoic acid; maternal behavior; regulation of heart rate; eating behavior; response to amphetamine; social behavior; sleep; response to ether; response to cocaine; memory; positive regulation of ossification; response to sucrose stimulus; positive regulation of synaptogenesis; positive regulation of prostaglandin secretion; sperm ejaculation; response to activity; regulation of sensory perception of pain; response to progesterone stimulus; positive regulation of blood pressure

size1 :

5 mg

price1 :

140 USD

size2 :

25 mg

price2 :

205

size3 :

100 mg

price3 :

450

more info or order :

MyBioSource product webpage