product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant HIV-2 gp32
catalog :
MBS142620
quantity :
0.1 mg
price :
225 USD
more info or order :
product information
catalog number :
MBS142620
products type :
Recombinant Protein
products full name :
Recombinant HIV-2 gp32
products short name :
HIV-2 gp32
products name syn :
HIV-2 gp32; HIV-2 gp32 Recombinant; HIV-2 gp32
host :
E Coli
specificity :
Immunoreactive with all sera of HIV-2 infected individuals.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
The HIV-2 gp32 solution (1mg/ml) 0.01M Na2CO3, 0.01M Na3EDTA, 0.014 M?-mercaptoethanol and 0.02% Sarcosyl. Sterile filtered colorless clear solution.
storage stability :
Protein should be stored at 4 degree C.Refrigerate Upon arrival. DO NOT FREEZE.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
HIV-2 gp32 antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
products categories :
VIRAL ANTIGENS- HUMAN IMMUNODEFICIENCY VIRUS; Viral Antigens; HIV
products description :
Description: HIV-2 gp32 recombinant- contains the full-length sequence of HIV-2 envelope immunodominant regions gp32. Introduction: HIV-1 and HIV-2 appear to package their RNA differently. HIV-1 binds to any appropriate RNA whereas HIV-2 preferentially binds to mRNA which creates the Gag protein itself. This means that HIV-1 is better able to mutate. HIV-2 is transmitted in the same ways as HIV-1: Through exposure to bodily fluids such as blood, semen, tears and vaginal fluids.Immunodeficiency develops more slowly with HIV-2.HIV-2 is less infectious in the early stages of the virus than with HIV-1.The infectiousness of HIV-2 increases as the virus progresses.Major differences include reduced pathogenicity of HIV-2 relative to HIV-1, enhanced immune control of HIV-2 infection and often some degree of CD4-independence. Despite considerable sequence and phenotypic differences between HIV-1 and 2 envelopes, structurally they are quite similar. Both membrane-anchored proteins eventually form the 6-helix bundles from the N-terminal and C-terminal regions of the ectodomain, which is common to many viral and cellular fusion proteins and which seems to drive fusion. HIV-1 gp41 helical regions can form more stable 6-helix bundles than HIV-2 gp41 helical regions however HIV-2 fusion occurs at a lower threshold temperature (25 degree C), does not require Ca2+ in the medium, is insensitive to treatment of target cells with cytochalasin B, and is not affected by target membrane glycosphingolipid composition.
size1 :
0.1 mg
price1 :
225 USD
size2 :
0.5 mg
price2 :
645
size3 :
1 mg
price3 :
1220
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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