protein

Synthetic HIV-2 gp36

MBS142593

0.1 mg

165 USD

Recombinant Protein

Synthetic HIV-2 gp36

Synthetic HIV-2 gp36

HIV-2 gp36; HIV-2 gp36 Synthetic; HIV-2 gp36

E Coli

Immunoreactive with all sera of HIV-2 infected individuals.

Greater than 95.0% as determined by HPLC.

(1mg/1ml) in H2O. Sterile filtered colorless clear solution.

ELISA (EIA), Western Blot (WB)

HIV-2 gp36 antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

VIRAL ANTIGENS- HUMAN IMMUNODEFICIENCY VIRUS; Viral Antigens; HIV

Description: HIV-2 gp36 is full length chemically synthesized polypeptide sequence of HIV-2 envelope immunodominant regions. Introduction: HIV-1 and HIV-2 appear to package their RNA differently. HIV-1 binds to any appropriate RNA whereas HIV-2 preferentially binds to mRNA which creates the Gag protein itself. This means that HIV-1 is better able to mutate. HIV-2 is transmitted in the same ways as HIV-1: Through exposure to bodily fluids such as blood, semen, tears and vaginal fluids. Immunodeficiency develops more slowly with HIV-2.HIV-2 is less infectious in the early stages of the virus han with HIV-1. The infectiousness of HIV-2 increases as the virus progresses. Major differences include reduced pathogenicity of HIV-2 relative to HIV-1, enhanced immune control of HIV-2 infection and often some degree of CD4-independence. Despite considerable sequence and phenotypic differences between HIV-1 and 2 envelopes, structurally they are quite similar. Both membrane-anchored proteins eventually form the 6-helix bundles from the N-terminal and C-terminal regions of the ectodomain, which is common to many viral and

0.1 mg

165 USD

0.5 mg

360

1 mg

550