product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Hepatitis C Virus Combined
catalog :
MBS142523
quantity :
0.1 mg
price :
225 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142523
products type :
Recombinant Protein
products full name :
Recombinant Hepatitis C Virus Combined
products short name :
Hepatitis C Virus Combined
products name syn :
HCV Combined; Hepatitis C Virus Combined Recombinant; HCV Combined
other names :
hepatitis C virus polyprotein; Genome polyprotein
products gene name :
HCV
other gene names :
HCV
uniprot entry name :
D5MTP0_9HEPC
sequence length :
3033
specificity :
Immunoreactive with sera of HCV-infected individuals.
purity :
HCV protein is >95% pure as determined by 10% PAGE (coomassie staining). HCV protein was purified by proprietary chromatographic technique.
form :
50mM Na-PO4, pH-8.5, 2.4mM EDTA, 5mM DTT and 0.1% SDS.
tested application :
ELISA (EIA), Western Blot (WB)
app notes :
HCV Antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
products categories :
VIRAL ANTIGENS- HEPATITIS C VIRUS; Viral Antigens; Hepatitis C
products description :
Description: The E Coli derived 70 kDa recombinant protein contains sequences from 4 gene products (proteins) of the hepatitis C virus (HCV) were scanned by using 3 different PCR-based techniques in search of the most immunoreactive regions suitable for the development of a diagnostic test for the detection of anti-HCV in human sera. All PCR fragments were cloned with pGEX4-2T expression vector and expressed in E Coli as chimeric proteins with glutathione S-transferase. The most diagnostically relevant proteins identified in this study were then contructed into one recombinant antigen. The protein contains the HCV nucleocapsid, NS3 genotype 1b, NS4 genotype 1b and 1a, and NS5 genotype 1b and 1a immunodominant regions. Introduction: HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
ncbi gi num :
295901482
ncbi acc num :
BAJ07247.1
ncbi mol weight :
330,337 Da
size1 :
0.1 mg
price1 :
225 USD
size2 :
0.5 mg
price2 :
645
size3 :
1 mg
price3 :
1030
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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