protein

Hyaluronidase

MBS142464

1500 IU

140 USD

Native Protein

Hyaluronidase

Hyaluronidase

HYAL1; Hyaluronidase; Hyaluronidase-1; EC 3.2.1.35; Hyal-1; Hyaluronoglucosaminidase-1; LUCA-1

hyaluronidase; Hyaluronidase-3; hyaluronidase-3; lung carcinoma protein 3; hyaluronoglucosaminidase 3; Hyaluronoglucosaminidase-3; Lung carcinoma protein 3; LuCa-3

oHYAL 1

HYAL3; HYAL3; LUCA3; HYAL-3; LUCA-3; LUCA3; Hyal-3; LuCa-3

HYAL3_HUMAN

Bovine Testis

463

The enzyme was lyophilized 1xPBS and 2% mannitol. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Hyaluronidase although although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Hyaluronidase should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Hyaluronidase in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Activity: 300 IU/mg.

ENZYMES; Enzymes; Natural Enzymes

Description: Hyaluronidase is an enzyme that temporarily and reversibly breaks down the polysaccharide, hyaluronic acid, which is found between the cells of connective tissue. Hyaluronic acid may be thought of as the "glue" that holds cells together. Hyaluronic acid is a mucopolysaccharide that exists in the human tissue matrix. It can constrain the diffusion of the extracellular fluid. Hyaluronidase makes the glucoseamine of the hyaluronic acid molecules hydrolyzed and depolymerized, thus decreases the viscosity of the body fluids and increases the flow and diffusion of the intercellular fluids. In this way the physic liquor, exudates or blood in local areas can be more easily diffused, and the drug can be more easily absorbed. Thus the local tissue tension and pains can be relieved. And it will also be easier for the edema and inflammatory exudates to be absorbed and dissolved. This product is a basic component of the articular cartilage. It can nourish, protect and maintain the functions of the joints.

2935328

AAC70915.1

15,865 Da

CS/DS Degradation Pathway 645311!!Chondroitin Sulfate Degradation Pathway 413376!!Chondroitin Sulfate Degradation Pathway 468247!!Chondroitin Sulfate/dermatan Sulfate Metabolism Pathway 645308!!Defective B3GAT3 Causes JDSSDHD Pathway 1127588!!Defective B4GALT1 Causes B4GALT1-CDG (CDG-2d) Pathway 1127592!!Defective B4GALT7 Causes EDS, Progeroid Type Pathway 1127587!!Defective CHST14 Causes EDS, Musculocontractural Type Pathway 1127591!!Defective CHST3 Causes SEDCJD Pathway 1127590!!Defective CHST6 Causes MCDC1 Pathway 1127593

This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and some isoforms may lack hyaluronidase activity. This gene overlaps and is on the same strand as N-acetyltransferase 6 (GCN5-related), and some transcripts of each gene share a portion of the first exon. [provided by RefSeq, Jan 2011]

1500 IU

140 USD