protein

Recombinant Human Neuronal Specific Enolase, His Tag

MBS142439

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Neuronal Specific Enolase, His Tag

Neuronal Specific Enolase

ENO2 Human, His; Neuron Specific Enolase Human Recombinant, His Tag; Gamma-enolase; EC 4.2.1.11; 2-phospho-D-glycerate hydro-lyase; Neural enolase; Neuron-specific enolase; NSE; Enolase 2; ENO2; ENO2, His

gamma-enolase; Gamma-enolase; gamma-enolase; 2-phospho-D-glycerate hydro-lyase; 2-phospho-D-glycerate hydrolyase; epididymis secretory protein Li 279; neural enolase; neuron specific gamma enolase; neuron-specific enolase; neurone-specific enolase; enolase 2 (gamma, neuronal); 2-phospho-D-glycerate hydro-lyase; Enolase 2; Neural enolase; Neuron-specific enolase; NSE

ENO2

ENO2; ENO2; NSE; HEL-S-279; NSE

ENOG_HUMAN

E Coli

434

Greater than 95% as determined by SDS-PAGE. Single band on Western Blot.

Enolase 2 is supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol. Sterile Filtered clear solution.

Store at 4 degree C if entire vial will be used within 1-2 weeks. Store, frozen at -20 degree C for longer periods of time. Please prevent freeze-thaw cycles.

ENZYMES; Enzymes; Enolase

Description: Neuron Specific Enolase Human Recombinant is expressed in E Coli containing 433 amino acids 2-434 fused to an amino terminal hexahistidine tag.The NSE is purified by proprietary chromatographic techniques. Introduction: NSE is the ?? isoform of the glycolytic enzyme enolase and is expressed primarily in neurons, in normal and neoplastic neuroendocrine cells. NSE is a highly soluble cytoplasmic protein that is readily secreted into the CSF and serum following tissue damage. NSE shows neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons and binds in a calcium-dependent manner to cultured neocortical neurons promoting cell survival.

5803011

NP_001966.1

NM_001975.2

P09104

42,707 Da

Biosynthesis Of Amino Acids Pathway (790012); Biosynthesis Of Amino Acids Pathway (795174); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Disease Pathway (530764); Gluconeogenesis Pathway (106204); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (413342); Gluconeogenesis, Oxaloacetate = Fructose-6P Pathway (468196); Glucose Metabolism Pathway (106199); Glycogen Storage Diseases Pathway (1127581)

This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. [provided by RefSeq, Jul 2008]

ENO2: an enzyme with 2-phospho-D-glycerate hydro-lyase activity. One of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates. Protein type: Lyase; EC 4.2.1.11; Carbohydrate Metabolism - glycolysis and gluconeogenesis. Chromosomal Location of Human Ortholog: 12p13. Cellular Component: extracellular space; phosphopyruvate hydratase complex; photoreceptor inner segment; plasma membrane; perikaryon; cytosol. Molecular Function: magnesium ion binding; phosphopyruvate hydratase activity. Biological Process: glycolysis; carbohydrate metabolic process; glucose metabolic process; pathogenesis; gluconeogenesis

0.002 mg

140 USD

0.01 mg

205

1 mg

4960