Recombinant Human Acetyl-Coenzyme A acetyltransferase 2 | MyBioSource MBS142436 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Acetyl-Coenzyme A acetyltransferase 2

catalog :

MBS142436

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS142436

products type :

Recombinant Protein

products full name :

Recombinant Human Acetyl-Coenzyme A acetyltransferase 2

products short name :

Acetyl-Coenzyme A acetyltransferase 2

products name syn :

ACAT2 Human; Acetyl-Coenzyme A acetyltransferase 2 Human Recombinant; Acetyl-CoA acetyltransferase cytosolic; Cytosolic acetoacetyl-CoA thiolase; ACAT2; Acetyl CoA transferase-like protein; ACAT-2

other names :

acetyl-CoA acetyltransferase, cytosolic isoform 1; Acetyl-CoA acetyltransferase, cytosolic; acetyl-CoA acetyltransferase, cytosolic; acetoacetyl Coenzyme A thiolase; acetyl-CoA transferase-like protein; cytosolic acetoacetyl-CoA thiolase; acetyl-CoA acetyltransferase 2; Acetyl-CoA transferase-like protein; Cytosolic acetoacetyl-CoA thiolase

products gene name :

ACAT2

other gene names :

ACAT2; ACAT2; ACTL

uniprot entry name :

THIC_HUMAN

host :

E Coli

sequence length :

397

purity :

Greater than 95.0% as determined by SDS-PAGE.

form :

ACAT2 Human solution containing 20mM Tris pH-8, 0.1M NaCl, 1mM DTT and 20% glycerol. Sterile Filtered clear solution.

concentration :

1mg/ml

storage stability :

ACAT2 Human although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. Please prevent freeze thaw cycles.

products categories :

ENZYMES; Enzymes; Transferase

products description :

Description: ACAT2 Recombinant Human produced in E Coli is a single, non-glycosylated polypeptide chain containing 433 amino acids (1-397 a.a.) and having a molecular mass of 45.4 kDa. The ACAT2 is fused to 36 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. Introduction: ACAT2 enzyme participates in lipid metabolism. ACAT2 takes part in lipoprotein assembly, catalyzing cholesterol esterification in mammalian cells. ACAT2 is an integral membrane protein that localizes to the endoplasmic reticulum of human intestinal cells. ACAT2 deficiency contributes to severe mental retardation and hypotonus.

ncbi gi num :

148539872

ncbi acc num :

NP_005882.2

ncbi gb acc num :

NM_005891.2

uniprot acc num :

Q9BWD1

ncbi mol weight :

44,643 Da

ncbi pathways :

Butanoate Metabolism Pathway (83007); Butanoate Metabolism Pathway (391); C5 Isoprenoid Biosynthesis, Mevalonate Pathway (413387); C5 Isoprenoid Biosynthesis, Mevalonate Pathway (468288); Carbon Metabolism Pathway (814926); Carbon Metabolism Pathway (817567); Fat Digestion And Absorption Pathway (194385); Fat Digestion And Absorption Pathway (194324); Fatty Acid Degradation Pathway (82935); Fatty Acid Degradation Pathway (296)

ncbi summary :

The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2014]

uniprot summary :

ACAT2: The product of this gene is an enzyme involved in lipid metabolism, and it encodes cytosolic acetoacetyl-CoA thiolase. This gene shows complementary overlapping with the 3-prime region of the TCP1 gene in both mouse and human. These genes are encoded on opposite strands of DNA, as well as in opposite transcriptional orientation. [provided by RefSeq, Jul 2008]. Protein type: Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Carbohydrate Metabolism - propanoate; Amino Acid Metabolism - lysine degradation; Lipid Metabolism - synthesis and degradation of ketone bodies; Carbohydrate Metabolism - pyruvate; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - tryptophan; Acetyltransferase; EC 2.3.1.9; Lipid Metabolism - fatty acid; Amino Acid Metabolism - valine, leucine and isoleucine degradation. Chromosomal Location of Human Ortholog: 6q25.3. Cellular Component: nucleoplasm; cytoplasm; nucleolus; nucleus. Molecular Function: acetyl-CoA C-acetyltransferase activity. Biological Process: lipid metabolic process. Disease: Acetyl-coa Acetyltransferase-2 Deficiency

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.02 mg

price2 :

205

size3 :

1 mg

price3 :

2665

more info or order :

MyBioSource product webpage