catalog number :
MBS142432
products type :
Recombinant Protein
products full name :
Recombinant Disulfide Bond Isomerase
products short name :
Disulfide Bond Isomerase
products name syn :
DsbC; Disulfide-Bond Isomerase Recombinant; DsbC; Thiol:disulfide interchange protein dsbC
other names :
protein disulfide isomerase II; Thiol:disulfide interchange protein DsbC; protein disulfide isomerase II
products gene name :
DsbC
other gene names :
dsbC; dsbC; ECK2888; JW2861; xprA; xprA
uniprot entry name :
DSBC_ECOLI
sequence :
DDAAIQQTLA KMGIKSSDIQ PAPVAGMKTV LTNSGVLYIT DDGKHIIQGP MYDVSGTAPVNVTNKMLLKQ LNALEKEMIV YKAPQEKHVI VFTDITCGY CHKLHEQMAD YNALGITVRYLAFPRQGLDS DAEKEMKAIW CAKDKNKAFD DVMAGKSVAP ASCDVDIADH YVLGVQLGVSGTPAVVLSNG TLVPGYQPPK EMKEFLDEHQ KMTSGK.
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
1 mg/ml solution containing 20mM phosphate buffer pH 7.5 and 20mM EDTA. Sterile filtered colorless solution.
storage stability :
Disulfide-Bond Isomerase Recombinant although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C.Please prevent freeze-thaw cycles.
products categories :
ENZYMES; Enzymes; Isomerase
products description :
Description: Disulfide-Bond Isomerase Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 216 amino acids (21-236) and having a molecular mass of 23.5 kDa.DsbC is purified by proprietary chromatographic techniques. Introduction: Dsb proteins (DsbA, DsbB, DsbC, and DsbD) catalyze formation and isomerization of protein disulfide bonds in the periplasm of Escherichia coli. DsbC is periplasmic enzyme known as a disulfide isomerase and can convert aberrant disulfide bonds to correct ones.
ncbi acc num :
NP_417369.1
ncbi gb acc num :
NC_000913.3
ncbi mol weight :
25,622 Da
ncbi summary :
DsbC rearranges incorrect disulfide bonds during oxidative protein folding. [More information is available at EcoGene: EG11070].