product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Yeast Isocitrate Dehydrogenase-1
catalog :
MBS142430
quantity :
1 mg
price :
140 USD
more info or order :
product information
catalog number :
MBS142430
products type :
Recombinant Protein
products full name :
Recombinant Yeast Isocitrate Dehydrogenase-1
products short name :
Isocitrate Dehydrogenase-1
products name syn :
IDH1; Isocitrate Dehydrogenase-1 Yeast Recombinant; Isocitrate dehydrogenase [NADP] cytoplasmic; EC 1.1.1.42; Cytosolic NADP-isocitrate dehydrogenase; Oxalosuccinate decarboxylase; IDH; NADP(+)-specific ICDH; IDP; PICD
other names :
isocitrate dehydrogenase; Peroxisomal isocitrate dehydrogenase [NADP]; isocitrate dehydrogenase
products gene name :
IDH1
other gene names :
ICDH; ICDH; F20D21.16; F20D21_16; ICDH; isocitrate dehydrogenase
uniprot entry name :
ICDHX_ARATH
host :
Yeast cells
sequence length :
416
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
One ml of solution contains 0.075 mol/l KPO4, 50% Glycerol, pH 7.1. Sterile Filtered clear solution.
other info1 :
Unit Defenition: One unit is defined as 1 umol of NAD+ production per minute under the assay conditions (25 degree C, pH 7.5).
other info2 :
Biological Activity: The specific activity was found to be 115 U/mg.
products categories :
ENZYMES; Enzymes; Dehydrogenase
products description :
Description: Recombinant Saccharomyces Cerevisiae ICDH (NADP) derived from yeast host cells by using over-expression system, is full length same as designated ICD1 from Saccharomyces Cerevisiae. The N-terminal amino acid Phenylalanine residue next to Met is substituted with Alanine for overexpression. The ICDH is purified by proprietary chromatographic techniques. Introduction: Isocitrate Dehydrogenase is an enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle.
ncbi gi num :
15221788
ncbi acc num :
NP_175836.1
ncbi gb acc num :
NM_104312.2
ncbi mol weight :
47,234 Da
ncbi pathways :
2-Oxocarboxylic Acid Metabolism Pathway (714629); 2-Oxocarboxylic Acid Metabolism Pathway (717400); Abnormal Conversion Of 2-oxoglutarate To 2-hydroxyglutarate Pathway (1118525); Biosynthesis Of Amino Acids Pathway (790118); Biosynthesis Of Amino Acids Pathway (795174); Biosynthesis Of Secondary Metabolites Pathway (148695); Carbon Metabolism Pathway (815031); Carbon Metabolism Pathway (817567); Citrate Cycle (TCA Cycle) Pathway (3985); Citrate Cycle (TCA Cycle) Pathway (288)
ncbi summary :
NADP-specific isocitrate dehydrogenase (ICDH)
size1 :
1 mg
price1 :
140 USD
size2 :
5 mg
price2 :
205
size3 :
50 mg
price3 :
1015
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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