protein

Recombinant Human Carbonic Anhydrase III, His Tag

MBS142411

0.005 mg

140 USD

Recombinant Protein

Recombinant Human Carbonic Anhydrase III, His Tag

Carbonic Anhydrase III

CAIII Human, His; Carbonic Anhydrase III Human Recombinant, His Tag; Car3; CAIII; Carbonic anhydrase 3; EC 4.2.1.1; Carbonic anhydrase III; Carbonate dehydratase III; CA-III; CA3 His

carbonic anhydrase 3; Carbonic anhydrase 3; carbonic anhydrase 3; CA-III; HEL-S-167mP; carbonate dehydratase III; carbonic anhydrase III, muscle specific; epididymis secretory sperm binding protein Li 167mP; carbonic anhydrase III; Carbonate dehydratase III; Carbonic anhydrase III; CA-III

CA3

CA3; CA3; Car3; CAIII; CA-III

CAH3_HUMAN

E Coli

260

Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Supplied in 10mM Tris-HCl (pH 8), 250mM NaCl, 0.5mM DTT, 1.5mM Cysteine, and 50% Glycerol. Sterile Filtered blue solution.

CAIII although stable at 4 degree C for 1 week, should be stored desiccated below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

ENZYMES; Enzymes; Carbonic Anhydrase

Description: Carbonic anhydrase III Human Recombinant produced in E Coli, and having a molecular mass of 33.9 kDa. CAIII is expressed with an amino-terminal hexahistidine tag.The CA-III is purified by proprietary chromatographic techniques. Introduction: Carbonic anhydrase (carbonate dehydratase) is a family of metalloenzymes (enzymes that contain one or more metal atoms as a functional component of the enzyme) that catalyze the rapid (and reversible) conversion of carbon dioxide to bicarbonate and protons, a reaction that occurs rather slowly in the absence of a catalyst. Carbonic anhydrase greatly increases the rate of the reaction, with typical catalytic rates of the different forms of this enzyme ranging between 104 and 106 reactions per second. The active site of most carbonic anhydrases contains a zincion. CAIII is a cytoplasmic isoenzyme, but is released into the circulation following injury.

4885099

NP_005172.1

NM_005181.3

P07451

29,557 Da

Metabolism Pathway (477135); Nitrogen Metabolism Pathway (83025); Nitrogen Metabolism Pathway (416); Reversible Hydration Of Carbon Dioxide Pathway (645352)

Carbonic anhydrase III (CAIII) is a member of a multigene family (at least six separate genes are known) that encodes carbonic anhydrase isozymes. These carbonic anhydrases are a class of metalloenzymes that catalyze the reversible hydration of carbon dioxide and are differentially expressed in a number of cell types. The expression of the CA3 gene is strictly tissue specific and present at high levels in skeletal muscle and much lower levels in cardiac and smooth muscle. A proportion of carriers of Duchenne muscle dystrophy have a higher CA3 level than normal. The gene spans 10.3 kb and contains seven exons and six introns. [provided by RefSeq, Oct 2008]

CA3: Reversible hydration of carbon dioxide. Belongs to the alpha-carbonic anhydrase family. Protein type: Lyase; Energy Metabolism - nitrogen; EC 4.2.1.1. Chromosomal Location of Human Ortholog: 8q21.2. Cellular Component: cytosol. Molecular Function: carbonate dehydratase activity; zinc ion binding; nickel ion binding. Biological Process: response to ethanol; bicarbonate transport; response to oxidative stress; one-carbon compound metabolic process

0.005 mg

140 USD

0.02 mg

205

1 mg

4005