product summary
Loading...
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Protein Phosphatase 4 Catalytic subunit
catalog :
MBS142407
quantity :
0.005 mg
price :
140 USD
more info or order :
product information
catalog number :
MBS142407
products type :
Recombinant Protein
products full name :
Recombinant Human Protein Phosphatase 4 Catalytic subunit
products short name :
Phosphatase 4
products name syn :
PPP4C Human; Protein Phosphatase 4 Catalytic subunit Human Recombinant; 800x600 800x600 Serine/threonine-protein phosphatase 4 catalytic subunit; PP4; PP4C; PPH3; PPP4; PPX; PPP4C; Protein Phosphatase 4 Catalytic subunit; Protein phosphatase X; PP-X; Pp4
other names :
serine/threonine-protein phosphatase 4 catalytic subunit isoform 1; Serine/threonine-protein phosphatase 4 catalytic subunit; serine/threonine-protein phosphatase 4 catalytic subunit; protein phosphatase 4 (formerly X), catalytic subunit; protein phosphatase X, catalytic subunit; protein phosphatase 4, catalytic subunit; Protein phosphatase X; PP-X
products gene name :
PPP4C
other gene names :
PPP4C; PPP4C; PP4; PPX; PP-X; PP4C; PPH3; PPP4; PPP4; PPX; PP4C; Pp4; PP-X
uniprot entry name :
PP4C_HUMAN
host :
E Coli
sequence length :
307
sequence :
800x600
purity :
Greater than 90% as determined by SDS-PAGE.
form :
800x600 The PPP4C solution (1mg/1ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.4M Urea and 10% glycerol. Sterile Filtered colorless solution.
products categories :
ENZYMES; Enzymes; Phosphatase
products description :
Description: 800x600 800x600 800x600 PPP4C Human Recombinant produced in E Coli is a single polypeptide chain containing 330 amino acids (1-307) and having a molecular mass of 37.5kDa. PPP4C is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: Protein Phosphatase 4 Catalytic subunit (PPP4C), is a part of the Serine/threonine-protein phosphatase catalytic subunits which tskes part in dephosphorylation and regulation of HDAC3. The protein phosphatase (PP) holoenzyme is a trimeric complex compound of a regulatory subunit, a variable subunit and a catalytic subunit. 4 major families of protein phosphatase catalytic subunits have been identified, designated PP1, PP2A, PP2B (calcineurin) and PP2C.
ncbi gi num :
4506027
ncbi acc num :
NP_002711.1
ncbi gb acc num :
NM_002720.2
uniprot acc num :
P60510
ncbi mol weight :
35,080 Da
uniprot summary :
PPP4C: a Ser/Thr phosphatase. A positive regulator of HPK1 and the HPK1-JNK signaling pathway. Mediates TNF-alpha-induced degradation of IRS-4 and plays a role in NF-kappaB p65 Thr dephosphorylation. Holoenzyme consists at least of a catalytic subunit PPP4C and a regulatory subunit PPP4R1. Protein type: Protein phosphatase, Ser/Thr (non-receptor); EC 3.1.3.16. Chromosomal Location of Human Ortholog: 16p11.2. Cellular Component: nucleoplasm; cytoplasm; plasma membrane; microtubule organizing center; nucleus. Molecular Function: NF-kappaB-inducing kinase activity; protein binding; metal ion binding; protein serine/threonine phosphatase activity. Biological Process: dephosphorylation
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.02 mg
price2 :
205
size3 :
1 mg
price3 :
2665
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!