catalog number :
MBS142389
products type :
Recombinant Protein
products full name :
Recombinant Rabbit Prolactin
products short name :
Prolactin
products name syn :
Prolactin Rabbit; Prolactin Rabbit Recombinant; Mammotropin; Luteotropic hormone; Luteotropin; PRL; raProlactin
other names :
prolactin; Prolactin; prolactin; N/A
other gene names :
PRL; PRL; PRL
uniprot entry name :
PRL_RABIT
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Leu-Pro-Ile-Cys.
purity :
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Prolactin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Prl should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Prolactin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 0.87 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of Prolactinl as a Reference Standard. Biological Activity: The ED50 as determined by the dose-dependant stimulation of the proliferation of rat lymphoma, Nb2-11 was found to be < 0.065ng/ml.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Prolactin
products description :
Description: Prolactin Rabbit Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 200 amino acids and having a molecular mass of 23007 Dalton. The Porlactin is purified by proprietary chromatographic techniques. Introduction: Prolactin is a neuroendocrine hormone synthesized primarily by the pituitary gland but also a variety of other cell types including the placenta, brain and uterus. Its primary function is to promote and maintain lactation but has also been shown to have a role in breast cancer development, regulation of reproductive function and immunoregulation.
ncbi acc num :
NP_001076144.1
ncbi gb acc num :
NM_001082675.1
ncbi mol weight :
25,990 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 1072805!!Cytokine-cytokine Receptor Interaction Pathway 460!!Jak-STAT Signaling Pathway 1073004!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 1072841!!Neuroactive Ligand-receptor Interaction Pathway 462!!PI3K-Akt Signaling Pathway 1072856!!PI3K-Akt Signaling Pathway 692979!!Prolactin Signaling Pathway 1072920!!Prolactin Signaling Pathway 814248