catalog number :
MBS142388
products type :
Recombinant Protein
products full name :
Recombinant Ovine Placental Lactogen
products short name :
Placental Lactogen
products name syn :
Placental Lactogen Ovine; Placental Lactogen Ovine Recombinant; Chorionic Somatomammotropin Hormone 1; CSH1; CS-1; hCS; PL; oPlacental Lactogen
other names :
Chorionic somatomammotropin hormone; Chorionic somatomammotropin hormone; chorionic somatomammotropin hormone; PL; Placental lactogen; PL
other gene names :
LOC443319; CSH; CSH; PL
uniprot entry name :
CSH_SHEEP
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Gln-His-Pro-Pro.
purity :
Greater than 98.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.02-0.03% NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Placental Lactogen Ovine Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Placental Lactogen should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Placental Lactogen in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: UV spectroscopy at 280 nm using the absorbency value of 0.85 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). Biological Activity: Placental Lactogen Ovine is biologically active as evidenced by inducing proliferation of Nb2 cells.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Placental Lactogen
products description :
Description: Placental Lactogen Ovine Recombinant, is a single polypeptide chain containing 199 amino acids and an additional Ala at the N-terminus having a molecular mass of 23 kDa. Placental Lactogen Recombinant is purified by proprietary chromatographic techniques. Introduction: Placental Lactogen is a polypeptide hormone that is produced by the Syncytiotrophoblasts of the Placenta, also known as chorionic somatomammotropin. It has both Growth Hormone and Prolactin activities on growth, lactation, and luteal steroid production. In women, placental lactogen secretion begins soon after implantation and increases to 1 g or more a day in late pregnancy. Placental lactogen is also an insulin antagonist.Placental Lactogen Ovine is also capable of activating human and other heterologous GH receptors but not ruminat GH receptors.
ncbi mol weight :
26,695 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 1030752!!Cytokine-cytokine Receptor Interaction Pathway 460!!Jak-STAT Signaling Pathway 1030801!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 1030753!!Neuroactive Ligand-receptor Interaction Pathway 462!!PI3K-Akt Signaling Pathway 1030766!!PI3K-Akt Signaling Pathway 692979!!Prolactin Signaling Pathway 1030835!!Prolactin Signaling Pathway 814248