product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Interleukin-10
catalog :
MBS142373
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142373
products type :
Recombinant Protein
products full name :
Recombinant Mouse Interleukin-10
products short name :
Interleukin-10
products name syn :
IL 10 Mouse; Interleukin-10 Mouse Recombinant; B-TCGF; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; Cytokine synthesis inhibitory factor
other names :
interleukin-10; Interleukin-10; interleukin-10; cytokine synthesis inhibitory factor; interleukin 10; Cytokine synthesis inhibitory factor; CSIF
products gene name :
mIL 10
other gene names :
Il10; Il10; CSIF; Il-10; Il-10; IL-10; CSIF
uniprot entry name :
IL10_MOUSE
host :
E Coli
sequence length :
178
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ser-Arg-Gly-Gln.
purity :
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized after extensive dialysis against PBS. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized IL-10 Mouse although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Interleukin10 Mouse recombinant should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized IL-10 Mouse Recombinant in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50 as determined by the dose-dependant co-stimulation with IL-4 of mouse MC-9 cells was found to be < 2ng/ml, corresponding to a Specific Activity of 500,000IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: IL-10 Recombinant Mouse produced in E Coli is a single, non-glycosylated polypeptide chain containing 161 amino acids and having a molecular mass of 18785 Dalton. The Interleukin-10 Mouse is purified by proprietary chromatographic techniques. Introduction: IL10 is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract.
ncbi gi num :
6754318
ncbi acc num :
NP_034678.1
ncbi gb acc num :
NM_010548.2
uniprot acc num :
P18893
ncbi mol weight :
20,641 Da
ncbi pathways :
African Trypanosomiasis Pathway 194387!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Amoebiasis Pathway 167330!!Amoebiasis Pathway 167191!!Asthma Pathway 83313!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83314!!Autoimmune Thyroid Disease Pathway 533
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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