product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Tumor Necrosis Factor-beta, His Tag
catalog :
MBS142371
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142371
products type :
Recombinant Protein
products full name :
Recombinant Human Tumor Necrosis Factor-beta, His Tag
products short name :
Tumor Necrosis Factor-beta
products name syn :
TNF b Human, His; Tumor Necrosis Factor-Beta Human Recombinant, His Tag; Lymphotoxin-alpha; LT-alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1; LTA; LT; TNFB; TNFSF1; TNF b His
other names :
lymphotoxin-alpha; Lymphotoxin-alpha; lymphotoxin-alpha; LT-alpha; TNF superfamily, member 1; TNF-beta; tumor necrosis factor beta; tumor necrosis factor ligand superfamily member 1; lymphotoxin alpha; TNF-beta; Tumor necrosis factor ligand superfamily member 1
products gene name :
TNF b
other gene names :
LTA; LTA; LT; TNFB; TNFSF1; TNFB; TNFSF1; LT-alpha
uniprot entry name :
TNFB_HUMAN
host :
E Coli
sequence length :
205
purity :
Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
TNF-b His is supplied in 20mM BTP, 50Mm NaCl and 50% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Tumor Necrosis Factor
products description :
Description: Tumor Necrosis Factor -b His Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 171 amino acids fragment (35-205) and having a molecular mass of 23.3kDa with an amino-terminal hexahistidine tag. The TNF-b His is purified by standard chromatographic techniques. Introduction: TNF-? is a potent multifunctional cytokine produced mainly by activated T and B lymphocytes. The protein has been shown to have a specific potent cytotoxic activity on tumor cells and a variety of other target cells as well as being a mediator of inflammation and immune function.
ncbi gi num :
6806893
ncbi acc num :
NP_000586.2
ncbi gb acc num :
NM_000595.3
uniprot acc num :
P01374
ncbi mol weight :
22,297 Da
ncbi pathways :
Apoptosis Pathway 198797!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Herpes Simplex Infection Pathway 377873!!Herpes Simplex Infection Pathway 377865!!IL2 Signaling Events Mediated By STAT5 Pathway 137988!!IL4-mediated Signaling Events Pathway 137933!!NF-kappa B Signaling Pathway 634527
ncbi summary :
The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4, myocardial infarction, non-Hodgkin's lymphoma, and psoriatic arthritis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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