product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interleukin-13, His Tag
catalog :
MBS142365
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142365
products type :
Recombinant Protein
products full name :
Recombinant Human Interleukin-13, His Tag
products short name :
Interleukin-13
products name syn :
IL 13 Human, His; Interleukin-13 Human Recombinant, His Tag; NC30; ALRH; BHR1; P600; IL-13; MGC116786; MGC116788; MGC116789; IL 13 His
other names :
interleukin-13; Interleukin-13; interleukin-13; interleukin 13; N/A
products gene name :
IL-13
other gene names :
IL13; IL13; P600; IL-13; NC30; IL-13
uniprot entry name :
IL13_HUMAN
host :
E Coli
sequence length :
146
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
Interleukin -13 His-Tag protein is supplied in 25mM Na-Acetate (pH 4.8) and 50% glycerol. Sterile Filtered clear solution.
concentration :
0.1 mg/ml
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-13 His Human Recombinant produced in E Coli is a single, non-glycosylated, Polypeptide chain containing 112 amino acids fragment (21-132) having a molecular weight of 12.84kDa with a 4kDa amino-terminal hexahistidine tag (total weight of 16.84kDa). The IL-13 His is purified by proprietary chromatographic techniques. Introduction: Interleukin-13 is a pleiotropic regulatory cytokine, which shares many of the properties of Interleukin-4. IL-13 is produced primarily by activated T lymphocytes and acts via specific cell surface receptor complexes. Its biological activities include the stimulation of B-cell proliferation and differentiation and the regulation of inflammatory and immune responses.
ncbi gi num :
26787978
ncbi acc num :
NP_002179.2
ncbi gb acc num :
NM_002188.2
uniprot acc num :
P35225
ncbi mol weight :
15,816 Da
ncbi pathways :
Asthma Pathway 83120!!Asthma Pathway 532!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response Pathway 198794!!Fc Epsilon RI Signaling Pathway 83082!!Fc Epsilon RI Signaling Pathway 493!!Glucocorticoid Receptor Regulatory Network Pathway 138014!!IL12 Signaling Mediated By STAT4 Pathway 137936!!Inflammatory Bowel Disease (IBD) Pathway 842771
ncbi summary :
This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells. This cytokine is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. [provided by RefSeq, Jul 2008]
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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