product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interleukin-10, His Tag
catalog :
MBS142362
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142362
products type :
Recombinant Protein
products full name :
Recombinant Human Interleukin-10, His Tag
products short name :
Interleukin-10
products name syn :
IL 10 Human, His; Interleukin-10 Human Recombinant, His; B-TCGF; CSIF; TGIF; IL-10; IL10A; MGC126450; MGC126451; Cytokine synthesis inhibitory factor; IL 10 His
other names :
interleukin-10; Interleukin-10; interleukin-10; T-cell growth inhibitory factor; cytokine synthesis inhibitory factor; interleukin 10; Cytokine synthesis inhibitory factor; CSIF
products gene name :
IL-10
other gene names :
IL10; IL10; CSIF; TGIF; GVHDS; IL-10; IL10A; IL-10; CSIF
uniprot entry name :
IL10_HUMAN
host :
E Coli
sequence length :
178
purity :
Greater than 95.0% by SDS-PAGE.
form :
Interleukin-10 His is supplied in 20mM Tris-HCl pH-8 and 20% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Introduction: Interleukin-10 is a multifunctional cytokine produced by a variety of cell types including T helper cells activated B cells and activated macrophages. Interleukin-10 regulates immune-mediated inflammation and modulates the function of cells such as lymphocytes, monocytes, natural killer cells and dendritic cells.
ncbi gi num :
10835141
ncbi acc num :
NP_000563.1
ncbi gb acc num :
NM_000572.2
uniprot acc num :
P22301
ncbi mol weight :
20,517 Da
ncbi pathways :
African Trypanosomiasis Pathway 194384!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 920963!!Allograft Rejection Pathway 83123!!Allograft Rejection Pathway 535!!Amoebiasis Pathway 167324!!Amoebiasis Pathway 167191!!Asthma Pathway 83120!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83121
ncbi summary :
The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis.[provided by RefSeq, May 2011]
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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