product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interleukin-7, His Tag
catalog :
MBS142361
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142361
products type :
Recombinant Protein
products full name :
Recombinant Human Interleukin-7, His Tag
products short name :
Interleukin-7
products name syn :
IL 7 Human, His; Interleukin-7 Human Recombinant, His Tag; Lymphopoietin 1 (LP-1); pre-B cell factor; IL-7; IL 7 His
other names :
interleukin-7 isoform 1; Interleukin-7; interleukin-7; interleukin 7; N/A
products gene name :
IL-7
other gene names :
IL7; IL7; IL-7; IL-7
uniprot entry name :
IL7_HUMAN
host :
E Coli
sequence length :
177
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Interleukin -7 His is supplied in 1x PBS and 50% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: IL-7 Human Recombinant produced in E Coli is single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 21.97 kDa with an amino-terminal hexahistidine tag. The IL-7 His-Tag protein is purified by proprietary chromatographic techniques. Introduction: Interleukin-7 is a potent lymphoid cell growth factor produced primarily by stromal cells.IL-7 has been shown to support the proliferation and differentiation of pre B- and early T cells as well as displaying a biological effect on cells of NK and myeloid lineages.
ncbi gi num :
4504677
ncbi acc num :
NP_000871.1
ncbi gb acc num :
NM_000880.3
uniprot acc num :
P13232
ncbi mol weight :
7,687 Da
ncbi pathways :
Cytokine Signaling In Immune System Pathway 366171!!Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!Immune System Pathway 106386!!Interleukin-7 Signaling Pathway 530762!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!PI3K-Akt Signaling Pathway 692234
ncbi summary :
The protein encoded by this gene is a cytokine important for B and T cell development. This cytokine and the hepatocyte growth factor (HGF) form a heterodimer that functions as a pre-pro-B cell growth-stimulating factor. This cytokine is found to be a cofactor for V(D)J rearrangement of the T cell receptor beta (TCRB) during early T cell development. This cytokine can be produced locally by intestinal epithelial and epithelial goblet cells, and may serve as a regulatory factor for intestinal mucosal lymphocytes. Knockout studies in mice suggested that this cytokine plays an essential role in lymphoid cell survival. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional splice variants have been described but their presence in normal tissues has not been confirmed.[provided by RefSeq, Dec 2010]
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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