catalog number :
MBS142352
products type :
Recombinant Protein
products full name :
Recombinant Human Granulocyte-Colony Stimulating Factor, His Tag
products short name :
Granulocyte-Colony Stimulating Factor
products name syn :
G CSF Human, His; Granulocyte-Colony Stimulating Factor Human Recombinant, His Tag; CSF-3; MGI-1G; GM-CSF beta; Pluripoietin; Filgrastim; Lenograstim; G-CSF; MGC45931; GCSF; G CSF His
other names :
granulocyte colony-stimulating factor isoform a; Granulocyte colony-stimulating factor; granulocyte colony-stimulating factor; filgrastim; granulocyte-colony stimulating factor; lenograstim; pluripoietin; colony stimulating factor 3 (granulocyte); Pluripoietin; INN: Filgrastim; INN: Lenograstim
products gene name :
G CSF
other gene names :
CSF3; CSF3; GCSF; CSF3OS; C17orf33; C17orf33; GCSF; G-CSF
uniprot entry name :
CSF3_HUMAN
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Granulocyte Colony Stimulating Factor His is supplied in 1x PBS and 50% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Colony Stimulating Factor
products description :
Description: Granulocyte Colony Stimulating Factor-His Tag Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 174 amino acids, fragment (31-204) and having a molecular mass of 23.19 kDa with an amino-terminal hexahistidine tag.G-CSF-His is purified by proprietary chromatographic techniques. Introduction: Granulocyte Colony Stimulating Factor is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of neutrophil granulocyte progenator cells and mature neutrophils.
ncbi acc num :
NP_000750.1
ncbi gb acc num :
NM_000759.3
ncbi mol weight :
18,434 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83051!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response Pathway 198794!!Hematopoietic Cell Lineage Pathway 83078!!Hematopoietic Cell Lineage Pathway 489!!Jak-STAT Signaling Pathway 83077!!Jak-STAT Signaling Pathway 488!!Malaria Pathway 152665!!Malaria Pathway 152657!!PI3K-Akt Signaling Pathway 692234
ncbi summary :
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes. The active protein is found extracellularly. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, May 2010]