MyBioSource

protein

Recombinant Mouse soluble CD40 Ligand/TRAP

MBS142348

1 mg

2665 USD

MBS142348

Recombinant Protein

Recombinant Mouse soluble CD40 Ligand/TRAP

soluble CD40 Ligand/TRAP

sCD40L Mouse; Soluble CD-40 Ligand/TRAP Mouse Recombinant; CD40-L; Tumor necrosis factor ligand superfamily member 5; TNF-related activation protein; TRAP; T cell antigen Gp39; CD154 antigen; sCD40; IGM; IMD3; HIGM1; T-BAM; TNFSF5; hCD40L

CD40 ligand; CD40 ligand; CD40 ligand; T-cell antigen Gp39; TNF-related activation protein; tumor necrosis factor ligand superfamily member 5; CD40 ligand; T-cell antigen Gp39; TNF-related activation protein; TRAP; Tumor necrosis factor ligand superfamily member 5; CD_antigen: CD154Cleaved into the following 2 chains:CD40 ligand, membrane form; CD40 ligand, soluble form

msCD40L

Cd40lg; Cd40lg; IGM; IMD3; Ly62; TRAP; gp39; CD154; Cd40l; HIGM1; Ly-62; T-BAM; CD40-L; Tnfsf5; Cd40l; Tnfsf5; CD40-L; TRAP

CD40L_MOUSE

E Coli

260

The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Arg-Gly-Asp.

Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

Lyophilized from a sterile concentrated solution (1mg/ml) with 10mM Sodium Phosphate pH=7.5. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized sCD40 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution CD154 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized sCD40 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50 as determined by its ability to induce MIP-1 alpha & TNF-alpha from mouse splenocytes was found to be 0.1 ug/ml corresponding to a Specific Activity of 10,000,000IU/mg.

CYTOKINES AND GROWTH FACTORS; CD Antigens

Description: sCD40 Mouse Recombinant produced in E Coli is a non-glycosylated, Polypeptide chain containing 149 amino acids and having a molecular mass of 16409 Dalton. The sCD40 is purified by proprietary chromatographic techniques. Introduction: CD40L or CD154 is a membrane glycoprotein and differentiation antigen expressed on the surface of T-cells. The CD40 ligand stimulates B-cell proliferation and secretion of all immunoglobulin isotypes in the presence of cytokines. CD40 ligand has been shown to induce cytokine production and tumoricidal activity in peripheral blood monocytes. It also costimulates proliferation of activated T-cells and this is accompanied by the production of IFN-gamma, TNF-alpha, and IL2.

15011846

NP_035746.2

NM_011616.2

P27548

29,370 Da

Adaptive Immune System Pathway 1110669!!Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Asthma Pathway 83313!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83314!!Autoimmune Thyroid Disease Pathway 533!!Cell Adhesion Molecules (CAMs) Pathway 83266!!Cell Adhesion Molecules (CAMs) Pathway 480!!Cytokine-cytokine Receptor Interaction Pathway 83248

1 mg

2665 USD