product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Ovine Growth Hormone Binding Protein
catalog :
MBS142346
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142346
products type :
Recombinant Protein
products full name :
Recombinant Ovine Growth Hormone Binding Protein
products short name :
Growth Hormone
products name syn :
GHBP Ovine; Growth Hormone Binding Protein Ovine Recombinant; GHR; GHBP; GH receptor; Somatotropin receptor
other names :
growth hormone receptor; Growth hormone receptor; growth hormone receptor; GH receptor; somatotropin receptor; Somatotropin receptorGrowth hormone-binding protein; GH-binding protein; GHBPAlternative name(s):Serum-binding protein
products gene name :
oGHBP
other gene names :
GHR; GHR; GH receptor; GH-binding protein; GHBP
uniprot entry name :
GHR_SHEEP
host :
E Coli
sequence length :
634
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Phe-Ser-Gly-Ser.
purity :
Greater than 95.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.
form :
GHBP was lyophilized from a concentrated (1mg/ml) solution with 0.0045mM NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Growth Hormone Binding Protein although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GHBP should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Growth Hormone Binding Protein in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Growth Hormone
products description :
Description: Growth Hormone Binding Protein Ovine Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 237 amino acids and having a molecular mass of 28 kDa. GHBP is purified by proprietary chromatographic techniques. Introduction: GHBP is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
ncbi gi num :
57164345
ncbi acc num :
NP_001009323.1
ncbi gb acc num :
NM_001009323.2
uniprot acc num :
Q28575
ncbi mol weight :
70,845 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 1030752!!Cytokine-cytokine Receptor Interaction Pathway 460!!Jak-STAT Signaling Pathway 1030801!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 1030753!!Neuroactive Ligand-receptor Interaction Pathway 462!!PI3K-Akt Signaling Pathway 1030766!!PI3K-Akt Signaling Pathway 692979
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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