protein

Recombinant Human Beta Defensin -3

MBS142337

0.005 mg

140 USD

Recombinant Protein

Recombinant Human Beta Defensin -3

Beta Defensin -3

BD 3 Human; Beta Defensin-3 Human Recombinant; HBD3; HBP3; DEFB3; HBD-3; HBP-3; DEFB103

beta-defensin 103; Beta-defensin 103; beta-defensin 103; beta defensin 3; beta defensin-3; beta-defensin 3; defensin, beta 103; defensin, beta 3; defensin-like protein; defensin, beta 103A; Beta-defensin 3; BD-3; DEFB-3; HBD3; hBD-3; Defensin, beta 103; Defensin-like protein

BD 3

DEFB103A; DEFB103A; BD-3; HBD3; HBP3; DEFB3; HBP-3; hBD-3; DEFB-3; DEFB103; BD3; DEFB103; DEFB3; BD-3; DEFB-3; HBD3; hBD-3

D103A_HUMAN

E Coli

67

GIINTLQKYY CRVRGGRCAV LSCLPKEEQI GKCSTRGRKC CRRKK.

Greater than 95.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

The HBD-3 was lyophilized without additives. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Beta Defensin-3 Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution BD-3 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Beta Defensin-3 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

CYTOKINES AND GROWTH FACTORS; Cytokines; Beta Defensin

Description: Beta Defensin-3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 45 amino acids and having a molecular mass of 5161.2 Dalton. The BD-3 is purified by proprietary chromatographic techniques. Introduction: Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103A, which has broad spectrum antimicrobial activity and may play an important role in innate epithelial defense.

125656159

NP_001075020.1

NM_001081551.3

P81534

7,697 Da

Beta Defensins Pathway (530759); Defensins Pathway (530757); Immune System Pathway (106386); Innate Immune System Pathway (106387)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]

defensin, beta 3: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. Belongs to the beta-defensin family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 8p23.1. Cellular Component: Golgi lumen; extracellular region. Biological Process: defense response to bacterium; innate immune response; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

0.005 mg

140 USD

0.02 mg

205

1 mg

1415