protein

Recombinant Human RELM-beta, His Tag

MBS142330

1 mg

3845 USD

Recombinant Protein

Recombinant Human RELM-beta, His Tag

RELM-beta

RELM b Human, His; RELM-Beta Human Recombinant, His Tag; Resistin-like beta; RELM beta; Cysteine-rich secreted protein FIZZ2; Colon and small intestine-specific cysteine-rich protein; Cysteine-rich secreted protein A12-alpha-like 1; Colon carcinoma-related gene protein; RELM-b; XCP2; HXCP2; RELM b His

resistin-like beta; Resistin-like beta; resistin-like beta; C/EBP-epsilon regulated myeloid-specific secreted cysteine-rich protein precursor 2; colon and small intestine-specific cysteine-rich protein; colon carcinoma-related gene protein; cysteine-rich secreted A12-alpha-like protein 1; cysteine-rich secreted protein A12-alpha-like 1; cysteine-rich secreted protein FIZZ2; found in inflammatory zone 1; resistin like beta; Colon and small intestine-specific cysteine-rich protein; Colon carcinoma-related gene protein; Cysteine-rich secreted protein A12-alpha-like 1; Cysteine-rich secreted protein FIZZ2; RELMbeta

RELM b

RETNLB; RETNLB; XCP2; FIZZ1; FIZZ2; HXCP2; RELMb; RELMbeta; RELM-beta; CCRG; FIZZ2; HXCP2; RETNL2

RETNB_HUMAN

E Coli

111

Greater than 95% as determined by SDS-PAGE.

Filtered and lyophilized from 0.5 mg/ml in 0.05M Acetate buffer pH-4. Filtered White lyophilized (freeze-dried) powder.

Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.

Solubility: Add 0.2 ml of 0.1M Acetate buffer pH-4 and let the lyophilized pellet dissolve completely. For conversion into higher pH value, we recommend intensive dilution by relevant buffer to a concentration of 10ug/ml. In higher concentrations the solubility of this antigen is limited.

CYTOKINES AND GROWTH FACTORS; Cytokines; Resistin

Description: RELM-beta Human Recombinant is a His-Tagged Fusion Protein which is 11 kDa protein containing 90 amino acid residues of the RELM-beta human and 12 additional amino acid residues - HisTag (underlined). Introduction: RELM-beta (Resistin-Like Molecule-beta) is a member of a recently identified family of secreted proteins containing a conserved cystein-rich C-terminus. The RELM family consists of resistin (also called FIZZ3), RELM-alfa (FIZZ1), RELM-beta (FIZZ2) and RELM-gamma. Only resisistin and RELM-beta were found in humans whereas all four RELM family members were identified in rodents.RELM-beta appears to be produced as a homodimer exclusively by intestinal goblet cells and can be found in high quantities in stool. Remarkably, stool of germ-free mice displaying sterile intestinal tract does not contain RELM-beta until bacterial colonization takes place after pathogen-free mice entered natural environment. Some, but not all, colon carcinoma cell lines secrete RELM-beta into the cell culture supernatant.The physiological function of RELM-beta is not known. High doses of recombinant RELM-beta showed hyperglycemic effects including lowered glucose disposal and increased hepatic glucose production in mice.

14211897

NP_115968.1

NM_032579.2

Q9BQ08

11,730 Da

IL4-mediated Signaling Events Pathway 137933

1 mg

3845 USD