product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Neuroglobin
catalog :
MBS142326
quantity :
0.002 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142326
products type :
Recombinant Protein
products full name :
Recombinant Human Neuroglobin
products short name :
Neuroglobin
products name syn :
NGB Human; Neuroglobin Human Recombinant; NGB
other names :
neuroglobin; Neuroglobin; neuroglobin; neuroglobin
products gene name :
NGB
other gene names :
NGB; NGB
uniprot entry name :
NGB_HUMAN
host :
E Coli
sequence length :
151
sequence :
MERPEPELIR QSWRAVSRSP LEHGTVLFAR LFALEPDLLP LFQYNCRQFS SPEDCLSSPE FLDHIRKVML VIDAAVTNVE DLSSLEEYLA SLGRKHRAVG VKLSSFSTVG ESLLYMLEKC LGPAFTPATR AAWSQLYGAV VQAMSRGWDG E.
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Filtered (0.4um) and lyophilized from 0.5 mg/ml in 0.05M phosphate buffer, 0.1M NaCl, pH 7.2. Filtered White lyophilized (freeze-dried) powder.
storage stability :
Store lyophilized protein at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
other info2 :
Solubility: It is recommended to add 200ul of deionized water to prepare a working stock solution of approximately 0.5mg/ml and let the lyophilized pellet dissolve completely. Neuroglobin is not sterile! Please filter the product by an appropriate sterile filter before suing it in the cell culture.
products categories :
CYTOKINES AND GROWTH FACTORS; Neurotrophins
products description :
Description: Neuroglobin Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 161 amino acids including a 10aa His tag at N-terminus. The total calculated molecular mass is 18 kDa.
ncbi gi num :
10864065
ncbi acc num :
NP_067080.1
ncbi gb acc num :
NM_021257.3
uniprot acc num :
Q9NPG2
ncbi mol weight :
18kDa
ncbi summary :
This gene encodes an oxygen-binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic/ischemic conditions. [provided by RefSeq, Jul 2008]
uniprot summary :
NGB: Involved in oxygen transport in the brain. Hexacoordinate globin, displaying competitive binding of oxygen or the distal His residue to the iron atom. Not capable of penetrating cell membranes. The deoxygenated form exhibits nitrite reductase activity inhibiting cellular respiration via NO-binding to cytochrome c oxidase. Involved in neuroprotection during oxidative stress. May exert its anti-apoptotic activity by acting to reset the trigger level of mitochondrial cytochrome c release necessary to commit the cells to apoptosis. Belongs to the globin family. Chromosomal Location of Human Ortholog: 14q24.3. Cellular Component: mitochondrion; perikaryon. Molecular Function: iron ion binding; heme binding; oxygen binding; oxygen transporter activity. Biological Process: apoptosis; oxygen transport
size1 :
0.002 mg
price1 :
140 USD
size2 :
0.01 mg
price2 :
205
size3 :
1 mg
price3 :
5435
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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