catalog number :
MBS142316
products type :
Native Protein
products full name :
Mouse beta Nerve Growth Factor
products short name :
beta Nerve Growth Factor
products name syn :
b NGF Mouse; Beta-Nerve Growth Factor Mouse; Beta Polypeptide; NGF; NGFB; HSAN5; Beta-NGF; MGC161426; MGC161428
other names :
beta-nerve growth factor isoform B; Beta-nerve growth factor; beta-nerve growth factor; beta-NGF; nerve growth factor, beta; nerve growth factor
products gene name :
mb NGF
other gene names :
Ngf; Ngf; Ngfb; Ngfb; Beta-NGF
uniprot entry name :
NGF_MOUSE
host :
Submaxillary Gland of Grown Mouse
sequence :
SSTHPVFHMGEF SVCDSVSVWV GDKTTATDIK GKEVTVLAEV NINNSVFRQY FFETKCRASN PVESGCRGID SKHWNSYCTT THTFVKALTT DEKQAAWRFI RIDTACVCVL SRKATRRG.
purity :
Greater than 98% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The NGF beta Mouse was lyophilized from solution containing 5% mannitol and 1% HSA. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Mouse Beta-NGF although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Murine NGF-Beta should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Murine NGF-beta in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The method used to test the bioassay is the NGF-dependent survival of dorsal root ganglia neurons of chick embryo, corresponding to a Specific Activity of 500,000IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Neurotrophins; Beta-Nerve Growth Factor
products description :
Description: NGF beta Mouse produced in Submaxillary Gland of Grown Mouse is a homodimer, non-glycosylated, polypeptide chain containing 2 identical 120 amino acids and having a molecular mass of 13,471 Dalton each.The NGF beta Mouse is purified by advanced biology purification technology. Introduction: NGF-beta has nerve growth stimulating activity and the complex is involved in the regulation of growth and the differentiation of sympathetic and certain sensory neurons. Mutations in this gene have been associated with hereditary sensory and autonomic neuropathy, type 5 (HSAN5), and dysregulation of this gene's expression is associated with allergic rhinitis.
products references :
V aron S, Raibo rn C. Dissociation, fractionation and culture ofchick embryo sympathetic ganglionic cells [ J ]. J N eu rocy tol, 1972; 1: 211- 221.
ncbi acc num :
NP_001106168.1
ncbi gb acc num :
NM_001112698.2
ncbi mol weight :
27,077 Da
ncbi pathways :
ARMS-mediated Activation Pathway 1110440!!Activation Of TRKA Receptors Pathway 1110431!!Apoptosis Pathway 83257!!Apoptosis Pathway 470!!Apoptosis Signaling Pathway 522973!!Axonal Growth Stimulation Pathway 1110427!!Cell Death Signalling Via NRAGE, NRIF And NADE Pathway 1110417!!Ceramide Signalling Pathway 1110425!!Frs2-mediated Activation Pathway 1110439!!Id Signaling Pathway 198411