product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Macrophage Colony Stimulating Factor
catalog :
MBS142315
quantity :
0.01 mg
price :
205 USD
more info or order :
product information
catalog number :
MBS142315
products type :
Recombinant Protein
products full name :
Recombinant Mouse Macrophage Colony Stimulating Factor
products short name :
Macrophage Colony Stimulating Factor
products name syn :
M CSF Mouse; Macrophage-Colony Stimulating Factor Mouse Recombinant; CSF-1; Lanimostim; MCSF; M-CSF
other names :
macrophage colony-stimulating factor 1 isoform 2; Macrophage colony-stimulating factor 1; macrophage colony-stimulating factor 1; osteopetrosis; colony stimulating factor 1 (macrophage); N/A
products gene name :
mM CSF
other gene names :
Csf1; Csf1; op; Csfm; MCSF; C87615; Csfm; CSF-1; MCSF
uniprot entry name :
CSF1_MOUSE
host :
E Coli
sequence length :
257
sequence :
MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP.
purity :
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized with 0.5xPBS, pH 8.0. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized M-CSF although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution MCSF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized M-CSF in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50, as calculated by the dose-dependant stimulation of the proliferation of murine M-NFS-60 indicator cells is typically 1.1-1.6ng/ml corresponding to 909,090-625,000 U/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Colony Stimulating Factor
products description :
Description: Macrophage Colony Stimulating Factor Mouse Recombinant produced in E Coli is a disulfide linked homodimer, non-glycosylated, polypeptide chain containing 2 x 156 amino acids and having a total molecular mass of 36.4 KD.MCSF is purified by proprietary chromatographic techniques. Introduction: Granulocyte/Macrophage Colony-Stimulating Factors are cytokines that act in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. CSF-1 induces cells of the monocyte/macrophage lineage. It plays a role in immunological defenses, bone metabolism, lipoproteins clearance, fertility and pregnancy.
ncbi gi num :
166064046
ncbi acc num :
NP_001107001.1
ncbi gb acc num :
NM_001113529.1
uniprot acc num :
P07141
ncbi mol weight :
29,353 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198283!!Hematopoietic Cell Lineage Pathway 83275!!Hematopoietic Cell Lineage Pathway 489!!Osteoclast Differentiation Pathway 193149!!Osteoclast Differentiation Pathway 193096!!PI3K-Akt Signaling Pathway 692242!!PI3K-Akt Signaling Pathway 692979!!Rap1 Signaling Pathway 869018
size :
0.01 mg
price :
205 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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