catalog number :
MBS142311
products type :
Recombinant Protein
products full name :
Recombinant Mouse Adiponectin glycosilated, HEK
products short name :
Adiponectin glycosilated
products name syn :
Acrp30 Mouse, HEK; Adiponectin Mouse Recombinant, HEK; Acrp30; AdipoQ; GBP-28; APM-1; ACDC; mAcrp30 HEK
other names :
adiponectin; Adiponectin; adiponectin; 30 kDa adipocyte complement-related protein; adipocyte complement related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; adipocyte-specific protein AdipoQ; adiponectin, C1Q and collagen domain containing; 30 kDa adipocyte complement-related protein; Adipocyte complement-related 30 kDa protein; ACRP30; Adipocyte, C1q and collagen domain-containing protein; Adipocyte-specific protein AdipoQ
products gene name :
mAcrp30
other gene names :
Adipoq; Adipoq; Ad; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30; Acdc; Acrp30; Apm1; ACRP30
uniprot entry name :
ADIPO_MOUSE
host :
HEK293 (Human embryonic kidney cell line)
sequence :
EDDVTTTEEL APALVPPPKG TCAGWMAGIP GHPGHNGTPG RDGRDGTPGE KGEKGDAGLL GPKGETGDVG MTGAEGPRGF PGTPGRKGEP GEAAYMYRSA FSVGLETRVT VPNVPIRFTK IFYNQQNHYD GSTGKFYCNI PGLYYFSYHI TVYMKDVKVS LFKKDKAVLF TYDQYQEKNV DQASGSVLLH LEVGDQVWLQ VYGDGDHNGL YADNVNDSTF TGFLLYHDTN DYKDDDDK.
purity :
Purity of adiponectin mouse recombinant is >98% (HPLC and SDS PAGE analyzed).
form :
Filtered (0.4 um) and lyophilized from 0.5 mg/ml in PBS buffer.
storage stability :
Store lyophilized APM-1 at -20 degree C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4 degree C for a limited period of time; it does not show any change after two weeks at 4 degree C.
other info2 :
Patent Rights: The sale and/or commercial use of Recombinant Adiponectin is prohibited in the United States of America (U.S.A). Solubility: It is recommended to reconstitute the lyophilized Acrp30 Mouse in sterile 18M-cm H2O at 0.5mg/ml, which can then be further diluted to other aqueous solutions. Biological Activity: Full-length mouse adiponectin activates AMP-activated protein kinase in hepatocyte and activates AMPK in HepG2 human hepatocytes at a concentration of 1000ng/ml corresponding to a Specific Activity of 1000IU/mg. Mouse adiponectin mammalian cell derived inhibits glucose production as shown by in-vitro gluconeogenesis assay in primary rat hepatocytes.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Adiponectin
products description :
Description: The Acrp30 Mouse Recombinant is fused with FLAG tag having a total Mw of 26kDa. Introduction: Adiponectin is an important negative regulator in hematopoiesis and immune systems. It may be involved in ending inflammatory responses through its inhibitory functions. Inhibits endothelial nf-kappa-b signaling through a camp-dependent pathway. Inhibits tnf-alpha- induced expression of endothelial adhesion molecules. Involved in the control of fat metabolism and insulin sensitivity.
ncbi acc num :
NP_033735.3
ncbi gb acc num :
NM_009605.4
ncbi mol weight :
26,809 Da
ncbi pathways :
AMPK Signaling Pathway 989651!!AMPK Signaling Pathway 992181!!Adipocytokine Signaling Pathway 83290!!Adipocytokine Signaling Pathway 505!!Adipogenesis Pathway 198299!!Leptin And Adiponectin Pathway 198344!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862220!!Non-alcoholic Fatty Liver Disease (NAFLD) Pathway 862314!!PPAR (Peroxisome Proliferator-activated Receptor) Signaling Pathway 522983!!PPAR Signaling Pathway 83239