product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Chicken Growth Hormone
catalog :
MBS142306
quantity :
0.02 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142306
products type :
Recombinant Protein
products full name :
Recombinant Chicken Growth Hormone
products short name :
Growth Hormone
products name syn :
GH Chicken; Growth Hormone Chicken Recombinant; GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin
other names :
somatotropin; Somatotropin; somatotropin; growth hormone 1; neural retina growth hormone; growth hormone; Growth hormone
products gene name :
chGH
other gene names :
GH; GH; GH1; N/A
uniprot entry name :
SOMA_CHICK
host :
E Coli
sequence length :
216
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Thr-Phe-Pro-Ala.
purity :
Greater than 99.0% as determined by: (a) Analysis by SDS-PAGE gel. (b) Analysis by SEC-HPLC.
form :
The protein was lyophilized from a concentrated (1mg/ml) solution with 0.3% NaHCO3 adjusted to pH 8. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized GH Chicken although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution at > 0.1 mg/ml and filter sterilization GH can be stored at 4 degree C for several weeks. At lower concentration addition of a carrier protein (0.1% HSA or BSA) is recomended.Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized GH Chicken Recombinant in sterile water or 0.4% NaHCO3 adjusted to pH 8-9, not less than 100 ug/ml and not more than 3 mg/ml, which can then be further diluted to other aqueous solutions, preferably in presence of carrier protein. Protein Content: Protein quantitation was carried out by two independent methods1. UV spectroscopy at 280 nm using the absorbency value of 0.75 as the extinction coefficient for a 0.1% (1mg/ml) solution at pH 8.0 This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of GH as a Reference Standard. Biological Activity: GH Chicken Recombinantis fully biologically active in homologous assays and in PDF-P1 3B9 cells stably transfected with rabbit GH receptors.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Growth Hormone
products description :
Description: Growth Hormone Chicken Recombinant (cGH) produced in E Coli is a single, non-glycosylated, polypeptide chain containing 191 amino acids with an additional Ala at its N-terminus and having a molecular mass of 22255 Dalton. GH Chicken recombinant is purified by proprietary chromatographic techniques. Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
ncbi gi num :
46048939
ncbi acc num :
NP_989690.1
ncbi gb acc num :
NM_204359.2
uniprot acc num :
P08998
ncbi mol weight :
24,713 Da
ncbi pathways :
Jak-STAT Signaling Pathway 83972!!Jak-STAT Signaling Pathway 488!!Neuroactive Ligand-receptor Interaction Pathway 119308!!Neuroactive Ligand-receptor Interaction Pathway 462
size :
0.02 mg
price :
140 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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