Recombinant Human Fibroblast Growth Factor-22 | MyBioSource MBS142304 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Fibroblast Growth Factor-22

catalog :

MBS142304

quantity :

0.002 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS142304

products type :

Recombinant Protein

products full name :

Recombinant Human Fibroblast Growth Factor-22

products short name :

Fibroblast Growth Factor-22

products name syn :

FGF 22 Human; Fibroblast Growth Factor-22 Human Recombinant; Fibroblast growth factor 22; FGF-22

other names :

fibroblast growth factor 22 isoform 1; Fibroblast growth factor 22; fibroblast growth factor 22; FGF-22; fibroblast growth factor 22

products gene name :

FGF 22

other gene names :

FGF22; FGF22; FGF-22

uniprot entry name :

FGF22_HUMAN

host :

E Coli

sequence length :

170

sequence :

MTPSASRGPR SYPHLEGDVR WRRLFSSTHF FLRVDPGGRV QGTRWRHGQD SILEIRSVHV GVVVIKAVSS GFYVAMNRRG RLYGSRLYTV DCRFRERIEE NGHNTYASQR WRRRGQPMFL ALDRRGGPRP GGRTRRYHLS AHFLPVLVS.

purity :

Greater than 97.0% as determined by(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

form :

The sterile protein powder is lyophilized with no additives. Sterile Filtered white lyophilized powder.

storage stability :

Lyophilized Fibroblast Growth Factor 22 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution FGF-22 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

other info2 :

Solubility: It is recommended to reconstitute the lyophilized Fibroblast Growth Factor-22 sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

products categories :

CYTOKINES AND GROWTH FACTORS; Growth Factors; Fibroblast Growth Factor

products description :

Description: Fibroblast Growth Factor-22 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 149 amino acids and having a molecular mass of 17.3 kDa. The FGF-22 is purified by chromatographic techniques. Introduction: FGF22 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development.

ncbi gi num :

10190672

ncbi acc num :

NP_065688.1

ncbi gb acc num :

NM_020637.1

uniprot acc num :

Q9HCT0

ncbi mol weight :

19,663 Da

ncbi pathways :

Activated Point Mutants Of FGFR2 Pathway (645281); Adaptive Immune System Pathway (366160); Constitutive PI3K/AKT Signaling In Cancer Pathway (685535); DAP12 Interactions Pathway (685549); DAP12 Signaling Pathway (685550); Disease Pathway (530764); Downstream Signal Transduction Pathway (106385); Downstream Signaling Events Of B Cell Receptor (BCR) Pathway (576250); Downstream Signaling Of Activated FGFR Pathway (160957); FGFR Ligand Binding And Activation Pathway (106344)

ncbi summary :

The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

uniprot summary :

FGF22: Plays a role in the fasting response, glucose homeostasis, lipolysis and lipogenesis. Can stimulate cell proliferation (in vitro). May be involved in hair development. Belongs to the heparin-binding growth factors family. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: Golgi apparatus; extracellular space; cell surface; nucleolus; extracellular region. Molecular Function: growth factor activity; fibroblast growth factor receptor binding. Biological Process: epidermal growth factor receptor signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; nerve growth factor receptor signaling pathway; insulin receptor signaling pathway; innate immune response; cell differentiation

size1 :

0.002 mg

price1 :

140 USD

size2 :

0.01 mg

price2 :

205

size3 :

1 mg

price3 :

5730

more info or order :

MyBioSource product webpage