product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Rabbit Insulin Like Growth Factor-1
catalog :
MBS142303
quantity :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142303
products type :
Recombinant Protein
products full name :
Recombinant Rabbit Insulin Like Growth Factor-1
products short name :
Insulin Like Growth Factor-1
products name syn :
IGF1 Rabbit; Insulin-Like Growth Factor 1 Rabbit Recombinant; Somatomedin C; IGF-I; IGFI; IGF1; IGF-IA; Mechano growth factor; MGF
other names :
insulin-like growth factor I; Insulin-like growth factor I; insulin-like growth factor I; IGF-I; insulin-like growth factor IB; somatomedin; Somatomedin
products gene name :
bIGF1
other gene names :
IGF1; IGF1; IGF-IB; IGF-1; IGF-I
uniprot entry name :
IGF1_RABIT
host :
E Coli
sequence length :
143
sequence :
MTAGPETLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKP
purity :
Greater than 98.0% as determined by: (a) Gel-filtration chromatography under non denaturing conditions. (b) Analysis by SDS-PAGE.
form :
The protein was lyophilized from a concentrated (0.5 mg/ml) solution with 0.02% NaHCO3. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Insulin-Like Growth Factor-1 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IGF1 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized rbIGF-I in sterile 0.4% NaHCO3 adjusted, not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: IGF-I is biologically active when compared to human IGF-1. The ED50, calculated by the dose -dependent proliferation of human MCF/7 cells is 5 to 25ng/ml in the cell culture mixture dependent on culture conditions. Its activity consists of 30-40 % compared to human IGF-1.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Insulin-Like Growth Factor
products description :
Description: Insulin-Like Growth Factor-I Rabbit Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 71 amino acids and having a molecular mass of 7639 Dalton. Introduction: The IGFs comprise a family of peptides that play important roles in mammalian growth and development. IGF1 mediates many of the growth-promoting effects of growth hormone. Early studies showed that growth hormone did not directly stimulate the incorporation of sulfate into cartilage, but rather acted through a serum factor, termed 'sulfation factor,' which later became known as 'somatomedin'. Three main somatomedins have been characterized: somatomedin C (IGF1), somatomedin A, and somatomedin B. IGF-1 is a small protein secreted mostly but not exclusively by the liver and circulating in blood mostly as a complex with several IGF binding proteins. It has growth-regulating, insulin-like, and mitogenic functions and it is secreted in response to growth hormone stimulation.
ncbi gi num :
126722801
ncbi acc num :
NP_001075495.1
ncbi gb acc num :
NM_001082026.1
uniprot acc num :
Q95222
ncbi mol weight :
15,205 Da
ncbi pathways :
AMPK Signaling Pathway 1072858!!AMPK Signaling Pathway 992181!!Aldosterone-regulated Sodium Reabsorption Pathway 1072928!!Aldosterone-regulated Sodium Reabsorption Pathway 130590!!Dilated Cardiomyopathy Pathway 1073002!!Dilated Cardiomyopathy Pathway 121285!!Focal Adhesion Pathway 1072873!!Focal Adhesion Pathway 478!!FoxO Signaling Pathway 1072840!!Glioma Pathway 1073007
size :
0.01 mg
price :
140 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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