catalog number :
MBS142286
products type :
Recombinant Protein
products full name :
Recombinant Mouse Granulocyte-Colony Stimulating Factor
products short name :
Granulocyte-Colony Stimulating Factor
products name syn :
G CSF Mouse; Granulocyte-Colony Stimulating Factor Mouse Recombinant; CSF3; MGI-1G; GM-CSF beta; Pluripoietin; G-CSF; GCSF; mG CSF
other names :
granulocyte colony-stimulating factor; Granulocyte colony-stimulating factor; granulocyte colony-stimulating factor; colony stimulating factor 3 (granulocyte); N/A
other gene names :
Csf3; Csf3; Csfg; G-CSF; MGI-IG; Csfg; G-CSF
uniprot entry name :
CSF3_MOUSE
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Val-Pro-Leu-Val.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
GCSF was lyophilized with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Granulocyte Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GCSF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Granulocyte Colony Stimulating Factor in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50 range=0.01-0.03 ng/ml corresponding to a Specific Activity of 33,4000,000-100,000,000IU/mg, determined by the dose-dependant proliferation of mouse NFS- 60cells. The optimal concentration for each specific application should be determined by an initial dose-response assay.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Colony Stimulating Factor
products description :
Description: Granulocyte Colony Stimulating Factor Mouse Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 179 amino acids and having a molecular mass of 19kDa.G-CSF is purified by proprietary chromatographic techniques. Introduction: Granulocyte Colony Stimulating Factor is a growth factor and/or cytokine produced by the endothelium, macrophages and a number of other immune cells. GCSF stimulates the bone marrow to produce granulocytes and also to stimulate the survival, proliferation, differentiation and function of neutrophil granulocyte progenator cells and mature neutrophils.
ncbi acc num :
NP_034101.1
ncbi gb acc num :
NM_009971.1
ncbi mol weight :
22,421 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198283!!Hematopoietic Cell Lineage Pathway 83275!!Hematopoietic Cell Lineage Pathway 489!!Jak-STAT Signaling Pathway 83274!!Jak-STAT Signaling Pathway 488!!Malaria Pathway 152666!!Malaria Pathway 152657!!PI3K-Akt Signaling Pathway 692242