catalog number :
MBS142280
products type :
Recombinant Protein
products full name :
Recombinant Canine Interferon-gamma
products short name :
Interferon-gamma
products name syn :
IFNG Canine; Interferon-gamma Canine Recombinant; Immune Interferon; type II interferon; T cell interferon; MAF; IFNG; IFG; IFI; IFN-gamma
other names :
interferon gamma; Interferon gamma; interferon gamma; interferon-gamma; N/A
products gene name :
k9IFNG
other gene names :
IFNG; IFNG; IFN-G; IFN-gamma; IFN-gamma
uniprot entry name :
IFNG_CANFA
sequence :
QAMFFKEIEN LKEYFNASNP DVSDGGSLFV DILKKWREES DKTIIQSQIV SFYLKLFDNF KDNQIIQRSM DTIKEDMLGK FLNSSTSKRE DFLKLIQIPV NDLQVQRKAI NELIKVMNDL SPRSNLRKRK RSQNLFRGRR ASK
purity :
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
The IFNG was lyophilized from a 0.2 um filtered concentrated solution in 25mM Sodium Succinate, pH 5.0, 60mM NaCl, with 0.1% Tween-80. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized IFNG although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IFNG should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized IFNG in sterile distilled H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by an anti-viral assay using A-72 canine fibroma cells infected with vesicular stomatitis virus (VSV) is less than 2.0 ng/ml, corresponding to a specific activity of > 5.0 x 105 IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interferon
products description :
Description: Recombinant IFNG Dog produced in E Coli cells is a non-glycosylated, homodimeric protein containing 143 amino acid chain and having a molecular mass of 16.9kDa. IFNG is purified by proprietary chromatographic techniques. Introduction: IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
ncbi acc num :
NP_001003174.1
ncbi gb acc num :
NM_001003174.1
ncbi mol weight :
19,395 Da
ncbi pathways :
African Trypanosomiasis Pathway 194390!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 84169!!Allograft Rejection Pathway 535!!Amoebiasis Pathway 167342!!Amoebiasis Pathway 167191!!Antigen Processing And Presentation Pathway 84124!!Antigen Processing And Presentation Pathway 485!!Chagas Disease (American Trypanosomiasis) Pathway 147812!!Chagas Disease (American Trypanosomiasis) Pathway 147795