product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Porcine Granulocyte Macrophage-Colony Stimulating Factor
catalog :
MBS142277
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142277
products type :
Recombinant Protein
products full name :
Recombinant Porcine Granulocyte Macrophage-Colony Stimulating Factor
products short name :
Granulocyte Macrophage-Colony Stimulating Factor
products name syn :
GM CSF Porcine; Granulocyte Macrophage-Colony Stimulating Factor Porcine Recombinant; CSF-2; MGI-1GM; GM-CSF; Pluripoietin-alpha; Molgramostin; Sargramostim
other names :
granulocyte-macrophage colony-stimulating factor; Granulocyte-macrophage colony-stimulating factor; granulocyte-macrophage colony-stimulating factor; CSF; Colony-stimulating factor; CSF
products gene name :
pGM CSF
other gene names :
CSF2; CSF2; GM-CSF; GM-CSF; CSF
uniprot entry name :
CSF2_PIG
host :
E Coli
sequence length :
144
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Pro-Thr-Arg-Pro.
purity :
Greater than 95.0% as determined by: (a)Analysis by RP-HPLC. (b)Analysis by SDS-PAGE.
form :
GM-CSF Porcine was lyophilized with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Granulocyte Macrophage Colony Stimulating Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GMCSF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Granulocyte Macrophage Colony Stimulating Factor in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: GMCSF quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.977 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of GM-CSF as a Reference Standard. Biological Activity: The ED50 range= 15-30ng/ml corresponding to a Specific Activity of 33,334-66,667IU/mg, determined by the dose dependent proliferation of TF-1 cells.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; Colony Stimulating Factor
products description :
Description: Granulocyte Macrophage Colony Stimulating Factor Porcine Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 127 amino acids and having a molecular mass of 14381 Dalton.GM-CSF Porcine Recombinant is purified by proprietary chromatographic techniques. Introduction: GMCSF is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13.GM-CSF stimulates the growth and differentiation of hematopoietic precursor cells from various lineages, including granulocytes, macrophages, eosinophils and erythrocytes.
ncbi gi num :
47523044
ncbi acc num :
NP_999283.1
ncbi gb acc num :
NM_214118.2
uniprot acc num :
Q29118
ncbi mol weight :
16,254 Da
ncbi pathways :
Amoebiasis Pathway 167313!!Amoebiasis Pathway 167191!!Cytokine Signaling In Immune System Pathway 1125176!!Cytokine-cytokine Receptor Interaction Pathway 84463!!Cytokine-cytokine Receptor Interaction Pathway 460!!Fc Epsilon RI Signaling Pathway 84494!!Fc Epsilon RI Signaling Pathway 493!!HTLV-I Infection Pathway 373897!!HTLV-I Infection Pathway 373889!!Hematopoietic Cell Lineage Pathway 84490
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!