product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human GDNF Family Receptor Alpha 3
catalog :
MBS142275
quantity :
0.005 mg
price :
140 USD
more info or order :
product information
catalog number :
MBS142275
products type :
Recombinant Protein
products full name :
Recombinant Human GDNF Family Receptor Alpha 3
products short name :
GDNF Family Receptor Alpha 3
products name syn :
GFRA3 Human; GDNF Family Receptor Alpha 3 Human Recombinant; GDNF Family Receptor Alpha3; GDNFR-alpha-3; GFR-alpha-3; GDNF Receptor Alpha-3; GDNFR3; GDNF Family Receptor Alpha-3; Glial Cell Line-Derived Neurotrophic Factor Receptor Alpha-3; GPI-Linked Receptor
other names :
GDNF family receptor alpha-3 preproprotein; GDNF family receptor alpha-3; GDNF family receptor alpha-3; GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3; GPI-linked receptor; glial cell line-derived neurotrophic factor receptor alpha-3; GDNF family receptor alpha 3
products gene name :
GFRA3
other gene names :
GFRA3; GFRA3; GDNFR3; GDNF receptor alpha-3; GDNFR-alpha-3; GFR-alpha-3
uniprot entry name :
GFRA3_HUMAN
host :
E Coli
sequence length :
400
purity :
Greater than 85% as determined by SDS-PAGE.
form :
GFRA3 protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH 8.0) 0.4M urea and 10% glycerol. Sterile Filtered clear solution.
storage stability :
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please avoid freeze thaw cycles.
products categories :
CYTOKINES AND GROWTH FACTORS; Neurotrophins; GDNF
products description :
Description: GFRA3 Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 366 amino acids (32-374a.a) and having a molecular mass of 40.7kDa.GFRA3 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. Introduction: GDNF Family Receptor Alpha 3 (GFRA3) belongs to the GDNF receptor family. GFRA3 creates a signaling receptor complex with RET tyrosine kinase receptor and
ncbi gi num :
22035694
ncbi acc num :
NP_001487.2
ncbi gb acc num :
NM_001496.3
uniprot acc num :
O60609
ncbi mol weight :
40,930 Da
ncbi summary :
The protein encoded by this gene is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. [provided by RefSeq, Jul 2008]
uniprot summary :
GFRA3: Receptor for the glial cell line-derived neurotrophic factor, ARTN (artemin). Mediates the artemin-induced autophosphorylation and activation of the RET receptor tyrosine kinase. Belongs to the GDNFR family. 2 isoforms of the human protein are produced by alternative splicing. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 5q31.1-q31.3. Cellular Component: extrinsic to membrane; intracellular membrane-bound organelle; cytoplasm; plasma membrane; external side of plasma membrane. Molecular Function: axon guidance receptor activity; receptor binding. Biological Process: nervous system development; axon guidance; sympathetic nervous system development; neuron migration; signal transduction; peripheral nervous system development
size1 :
0.005 mg
price1 :
140 USD
size2 :
0.02 mg
price2 :
205
size3 :
1 mg
price3 :
2665
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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