product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Rat Interleukin-5
catalog :
MBS142264
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142264
products type :
Recombinant Protein
products full name :
Recombinant Rat Interleukin-5
products short name :
Interleukin-5
products name syn :
IL 5 Rat; Interleukin-5 Rat Recombinant; EDF; BCDFII; TRF; T-cell replacing factor; Eosinophil differentiation factor; B cell differentiation factor I; IL-5
other names :
Interleukin-5; Interleukin-5; interleukin-5; B-cell growth factor II; BCGF-II; IL-5; Interleukin 5 (colony-stimulating factor eosinophil); Interleukin 5 (colony-stimulating factor, eosinophil); T-cell replacing factor; TRF; cytotoxic T-lymphocyte inducer; eosinophil differentiation factor; interleukin 5; B-cell growth factor II; BCGF-II; Cytotoxic T-lymphocyte inducer; Eosinophil differentiation factor; T-cell replacing factor; TRF
products gene name :
rIL 5
other gene names :
Il5; Il5; Il-5; IL-5; BCGF-II; TRF
uniprot entry name :
IL5_RAT
host :
E Coli
sequence length :
132
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Glu-Ile-Pro-Met.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a concentrated (1mg/ml) solution in water containing no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interleukin-5 Rat although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL5 Rat should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please avoid freeze thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Interleikin-5 Rat in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50 range=0.3-1.0 ng/ml as determined by the dose-dependant stimulation of the proliferation of BCL-1 cells.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-5 Rat Recombinant produced in E Coli is a dimeric, non-glycosylated polypeptide chain containing 113 amino acids and having a molecular mass of 13074 Dalton.The IL-5 is purified by proprietary chromatographic techniques. Introduction: The protein encoded by this gene is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. This cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of this cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. This cytokine, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
ncbi gi num :
585311
ncbi acc num :
Q08125.1
uniprot acc num :
Q08125
ncbi mol weight :
15,207 Da
ncbi pathways :
Allograft Rejection Pathway 83511!!Allograft Rejection Pathway 535!!Asthma Pathway 83508!!Asthma Pathway 532!!Autoimmune Thyroid Disease Pathway 83509!!Autoimmune Thyroid Disease Pathway 533!!Cytokine Signaling In Immune System Pathway 1121619!!Cytokine-cytokine Receptor Interaction Pathway 83443!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198521
ncbi summary :
cytokine with B-cell growth factor activity [RGD, Feb 2006]
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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