catalog number :
MBS142260
products type :
Recombinant Protein
products full name :
Recombinant Rat Interleukin-3
products short name :
Interleukin-3
products name syn :
IL 3 Rat; Interleukin-3 Rat Recombinant; MCGF (Mast cell growth factor); Multi-CSF; HCGF; P-cell stimulation factor; IL-3; MGC79398; MGC79399
other names :
Interleukin-3; Interleukin-3; interleukin-3; IL-3; MCGF; P-cell-stimulating factor; hematopoietic growth factor; mast cell growth factor; multipotential colony-stimulating factor; interleukin 3; Hematopoietic growth factor; Mast cell growth factor; MCGF; Multipotential colony-stimulating factor; P-cell-stimulating factor
products gene name :
rIL 3
other gene names :
Il3; Il3; Il-3; IL-3; MCGF
uniprot entry name :
IL3_RAT
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ser-Asp-Arg-Gly.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a 1mg/ml solution without any additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interleukin-3 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL3 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Interleukin 3 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50= 3-10 ng/ml corresponding to a specific activity of 100,000-333,334IU/mg determined by the dose dependent proliferation of murine NFS-60 cells.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-3 Rat Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 140 amino acids and having a molecular mass of 16 kDa. The IL-3 is purified by proprietary chromatographic techniques. Introduction: Interleukin-3 is a pleiotropic cytokine produced primarily by activated T cells. IL-3 is thought to function via specific cell surface receptors to stimulate the proliferation, differentiation and survival of haematopoietic cell lines. IL-3 has also been shown to affect the functional activity of a variety of other cell types including mast cells, eosinophils, megakaryocytes and basophils.
ncbi mol weight :
18,631 Da
ncbi pathways :
Apoptosis Pathway 83452!!Apoptosis Pathway 470!!Asthma Pathway 83508!!Asthma Pathway 532!!Cytokine-cytokine Receptor Interaction Pathway 83443!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198521!!Fc Epsilon RI Signaling Pathway 83474!!Fc Epsilon RI Signaling Pathway 493!!Hematopoietic Cell Lineage Pathway 83470
ncbi summary :
cytokine that functions as a multi-lineage haemopoietic growth regulator [RGD, Feb 2006]