product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Interleukin-2
catalog :
MBS142247
quantity :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142247
products type :
Recombinant Protein
products full name :
Recombinant Mouse Interleukin-2
products short name :
Interleukin-2
products name syn :
IL 2 Mouse; Interleukin-2 Mouse Recombinant; Interleukin-2; T-cell growth factor (TCGF); Aldesleukin; Lymphokine; IL-2
other names :
interleukin-2; Interleukin-2; interleukin-2; T-cell growth factor; TCGF; interleukin 2; T-cell growth factor; TCGF
products gene name :
mIL 2
other gene names :
Il2; Il2; Il-2; Il-2; IL-2; TCGF
uniprot entry name :
IL2_MOUSE
host :
E Coli
sequence length :
169
sequence :
PTSSSTSSST AEAQQQQQQQ QQQQQHLEQL LMDLQELLSR MENYRNLKLP RMLTFKFYLP KQATELKDLQ CLEDELGPLR HVLDLTQSKS FQLEDAENFI SNIRVTVVKL KGSDNTFECQ FDDESATVVD FLRRWIAFCQ SIISTSPQ.
purity :
Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a 0.2 um filtered concentrated solution (1mg/ml) in 20mM PBS, pH 7.4. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interleukin-2 although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IL2 should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Mouse IL-2 in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Protein Content: Protein quantitation was carried out by two independent methods:1. UV spectroscopy at 280 nm using the absorbency value of 0.482 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of IL-2 as a Reference Standard. Biological Activity: The ED50 as determined by the dose-dependant stimulation of murine CTLL-2 cells is less than 0.2ng/ml corresponding to a Specific Activity of 5x106IU/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interleukin
products description :
Description: Interleukin-2 Mouse Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 148 amino acids and having a molecular mass of 17.2kDa. The IL-2 is purified by proprietary chromatographic techniques. Introduction: IL2 is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.
ncbi gi num :
7110653
ncbi acc num :
NP_032392.1
ncbi gb acc num :
NM_008366.3
uniprot acc num :
P04351
ncbi mol weight :
19,400 Da
ncbi pathways :
Allograft Rejection Pathway 83316!!Allograft Rejection Pathway 535!!Autoimmune Thyroid Disease Pathway 83314!!Autoimmune Thyroid Disease Pathway 533!!Chagas Disease (American Trypanosomiasis) Pathway 147810!!Chagas Disease (American Trypanosomiasis) Pathway 147795!!Cytokine Signaling In Immune System Pathway 1110778!!Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Cytokines And Inflammatory Response (BioCarta) Pathway 198283
size :
0.02 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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