catalog number :
MBS142236
products type :
Recombinant Protein
products full name :
Recombinant Rat Interferon-gamma
products short name :
Interferon-gamma
products name syn :
IFN g Rat; Interferon-Gamma Rat Recombinant; Immune Interferon; type II interferon; T cell interferon; MAF; IFNG; IFG; IFI; IFN-gamma
other names :
interferon gamma; Interferon gamma; interferon gamma; IFN-gamma; interferon gamma; N/A
products gene name :
rIFNG
other gene names :
Ifng; Ifng; IFNG2; IFN-gamma
uniprot entry name :
IFNG_RAT
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Gln-Gly-Tyr-Leu.
purity :
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from a 0.2um filtered concentrated (1mg/ml) solution in PBS, pH 7.4. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Interferon-gamma although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution IFN-gamma should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Interferon-gamma in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The specific activity as determined by the cytopathic affect inhibition assay with murine L929 cells chalenged with EMC virus was < 0.1 ng/ml, corresponding to a specific activity of 10,000,000units/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Interferon
products description :
Description: Interferon-gamma Rat Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 135 amino acids and having a molecular mass of 15609 Dalton.The IFN-gamma is purified by proprietary chromatographic techniques. Introduction: IFN-gamma produced by lymphocytes activated by specific antigens or mitogens.IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages, and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.
ncbi acc num :
NP_620235.1
ncbi gb acc num :
NM_138880.2
ncbi mol weight :
17,918 Da
ncbi pathways :
African Trypanosomiasis Pathway 194377!!African Trypanosomiasis Pathway 194323!!Allograft Rejection Pathway 83511!!Allograft Rejection Pathway 535!!Amoebiasis Pathway 167311!!Amoebiasis Pathway 167191!!Antigen Processing And Presentation Pathway 83466!!Antigen Processing And Presentation Pathway 485!!Chagas Disease (American Trypanosomiasis) Pathway 147806!!Chagas Disease (American Trypanosomiasis) Pathway 147795
ncbi summary :
an immune molecule produced by T lymphocytes in response to mitogens or antigens [RGD, Feb 2006]