product summary
request information :
company name :
MyBioSource
product type :
protein
product name :
Recombinant Mouse Thrombopoietin
catalog :
MBS142223
quantity :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS142223
products type :
Recombinant Protein
products full name :
Recombinant Mouse Thrombopoietin
products short name :
Thrombopoietin
products name syn :
TPO Mouse; Thrombopoietin Mouse Recombinant; Megakaryocyte colony-stimulating factor; Myeloproliferative leukemia virus oncogene ligand; C-mpl ligand; ML; Megakaryocyte growth and development factor; MGDF; TPO; MKCSF; MPLLG; MGC163194; THPO
other names :
thrombopoietin isoform 1; Thrombopoietin; thrombopoietin; C-mpl ligand; megakaryocyte colony-stimulating factor; megakaryocyte growth and development factor; myeloproliferative leukemia virus oncogene ligand; thrombopoietin; C-mpl ligand; ML; Megakaryocyte colony-stimulating factor; Megakaryocyte growth and development factor; MGDF; Myeloproliferative leukemia virus oncogene ligand
products gene name :
mTPO
other gene names :
Thpo; Thpo; Ml; Tpo; Mgdf; Mpllg; ML; MGDF
uniprot entry name :
TPO_MOUSE
host :
E Coli
sequence length :
356
sequence :
SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF.
purity :
Greater than 95.0% as determined by SDS-PAGE.
form :
Lyophilized from a concentrated (1mg/ml) solution in water containing no additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Thrombopoietin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution TPO Mouse should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Thrombopoietin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: ED50 range is less than 0.8 ng/ml as determined by the dose dependent stimulation of Mo7e cells.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Thrombopoietin
products description :
Description: Thrombopoietin Mouse Recombinant produced in E Coli is a single, non-glycosylated soluble polypeptide chain containing 174 amino acids and having a molecular mass of 18704 Dalton. The TPO is purified by proprietary chromatographic techniques. Introduction: Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidneyt hat regulates the production of platelets by the bone marrow. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.
ncbi gi num :
291045237
ncbi acc num :
NP_001166976.1
ncbi gb acc num :
NM_001173505.1
uniprot acc num :
P40226
ncbi mol weight :
37,384 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Hematopoietic Cell Lineage Pathway 83275!!Hematopoietic Cell Lineage Pathway 489!!Hemostasis Pathway 1110026!!Jak-STAT Signaling Pathway 83274!!Jak-STAT Signaling Pathway 488!!Platelet Aggregation (Plug Formation) Pathway 1110044!!Platelet Activation, Signaling And Aggregation Pathway 1110036
ncbi summary :
This gene encodes a humoral growth factor necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. The encoded protein is a ligand for the product of the myeloproliferative leukemia virus oncogene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2010]
size :
0.01 mg
price :
205 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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