product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Platelet Derived Growth Factor-AB
catalog :
MBS142219
quantity :
0.01 mg
price :
205 USD
more info or order :
product information
catalog number :
MBS142219
products type :
Recombinant Protein
products full name :
Recombinant Human Platelet Derived Growth Factor-AB
products short name :
Platelet Derived Growth Factor-AB
products name syn :
PDGF AB Human; Platelet-Derived Growth Factor AB Human Recombinant; Glioma-derived growth factor; GDGF; Osteosarcoma-derived Growth Factor; ODGF; PDGF-AB
other names :
platelet-derived growth factor subunit A; Platelet-derived growth factor subunit A; platelet-derived growth factor subunit A; PDGF subunit A; PDGF-1; platelet-derived growth factor A chain, long form; platelet-derived growth factor alpha polypeptide<; PDGF-1; Platelet-derived growth factor A chain; Platelet-derived growth factor alpha polypeptide
products gene name :
PDGF AB
other gene names :
pdgfa; pdgfa; pdgf; pdgf-a; PDGF subunit A
uniprot entry name :
PDGFA_XENLA
host :
E Coli
sequence length :
226
sequence :
The sequence of the first five N-terminal amino acids was determined and was found to be Met-Ser-Ile-Glu-Glu-alpha chain and Met-Ser-Leu-Gly-Ser-beta chain.
purity :
Greater than 98.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
form :
Lyophilized from 10mM Acetic Acid. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Platelet-derived Growth Factor AB although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution PDGF-AB should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Platelet-derived Growth Factor-AB in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50, calculated by the dose-dependant proliferation of murine BALB/c 3T3 indicator cells (measured by 3H-thymidine uptake) is < 1 ng/ml, corresponding to a Specific Activity of 1,000,000units/mg.
products categories :
CYTOKINES AND GROWTH FACTORS; Growth Factors; PDGF
products description :
Description: Platelet-Derived Growth Factor AB Human Recombinant is a heterodimeric, non-glycosylated, polypeptide chain containing 234 amino acids consisting of 13.3kDa alpha-chain and 12.2 beta-chain having a total molecular mass of 25.5kDa. PDGF-AB is purified by proprietary chromatographic techniques. Introduction: The term ˜PDGF' refers to a family of disulphide bond-linked dimeric isoforms that act as autocrine and paracrine growth factors and are produced by a variety of cell types other than platelets.They act as potent mitogens for almost all mesenchymally-derived cells. Aberrant expression is involved in certain cancers, fibroproliferative disorders and atherosclerosis. The protein also contributes to wound healing and neural regeneration. There are four members of the PDGF family PDGF A, PDGF B, PDGF C and PDGF D. Two distinct types of PDGF-A exist a short form that is soluble and a long form that is retained by the extracellular matrix.
ncbi gi num :
148231109
ncbi acc num :
NP_001081304.1
ncbi gb acc num :
NM_001087835.1
ncbi mol weight :
22,833 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 119282!!Cytokine-cytokine Receptor Interaction Pathway 460!!Focal Adhesion Pathway 119287!!Focal Adhesion Pathway 478!!Gap Junction Pathway 119292!!Gap Junction Pathway 483!!MAPK Signaling Pathway 84645!!MAPK Signaling Pathway 456!!Regulation Of Actin Cytoskeleton Pathway 119294!!Regulation Of Actin Cytoskeleton Pathway 500
size :
0.01 mg
price :
205 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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