catalog number :
MBS142217
products type :
Recombinant Protein
products full name :
Recombinant Mouse Flt3-Ligand
products short name :
Flt3-Ligand
products name syn :
Flt3 Ligand Mouse; Flt3 Ligand Mouse Recombinant; Fms-related tyrosine kinase 3 ligand; FLK2; STK1; CD135; Stem Cell Tyrosine Kinase 1; FLT3LG; Flt3; mFlt3 Ligand
other names :
fms-related tyrosine kinase 3 ligand; Fms-related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; flt3 ligand; FMS-like tyrosine kinase 3 ligand; SL cytokine
other gene names :
Flt3l; Flt3lg; Ly72L; Flt3lg; Flt3l; Flt3 ligand; Flt3L
uniprot entry name :
FLT3L_MOUSE
sequence :
MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ.
purity :
Greater than 98.0% as determined by SDS-PAGE.
form :
The FLT3L Mouse protein was lyophilized without any additives. Sterile Filtered White lyophilized (freeze-dried) powder.
storage stability :
Lyophilized Flt3-Ligand although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Flt-3 Ligand should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.
other info2 :
Solubility: It is recommended to reconstitute the lyophilized Flt3-Ligand in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions. Biological Activity: The ED50, calculated by the dose-dependent proliferation of mouse AML5 cells is 1.3-2.0ng/ml.
products categories :
CYTOKINES AND GROWTH FACTORS; Cytokines; Flt3 Ligand
products description :
Description: Flt3-Ligand Mouse Recombinant produced in E Coli is non-glycosylated, polypeptide chain containing 163 amino acids and having a molecular mass of 18587 Dalton. Flt3-Ligand is purified by proprietary chromatographic techniques. Introduction: FLT3 ligand is a receptor for the fl cytokine has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation.
ncbi acc num :
NP_038548.3
ncbi gb acc num :
NM_013520.3
ncbi mol weight :
28,259 Da
ncbi pathways :
Cytokine-cytokine Receptor Interaction Pathway 83248!!Cytokine-cytokine Receptor Interaction Pathway 460!!Hematopoietic Cell Lineage Pathway 83275!!Hematopoietic Cell Lineage Pathway 489!!Pathways In Cancer 83298