Recombinant Human Endocrine Gland Vascular Endothelial Growth Factor | MyBioSource MBS142215 product information

product summary

company name :

MyBioSource

product type :

protein

product name :

Recombinant Human Endocrine Gland Vascular Endothelial Growth Factor

catalog :

MBS142215

quantity :

0.005 mg

price :

140 USD

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS142215

products type :

Recombinant Protein

products full name :

Recombinant Human Endocrine Gland Vascular Endothelial Growth Factor

products short name :

Endocrine Gland Vascular Endothelial Growth Factor

products name syn :

EG VEGF Human; Endocrine Gland Vascular Endothelial Growth Factor Human Recombinant; PK1; PRK1; Prokineticin 1; EG-VEGF; EG VEGF

other names :

prokineticin-1; Prokineticin-1; prokineticin-1; EG-VEGF; black mamba toxin-related protein; endocrine-gland-derived vascular endothelial growth factor; mambakine; prokineticin 1; Endocrine-gland-derived vascular endothelial growth factor; EG-VEGF; Mambakine

products gene name :

other gene names :

PROK1; PROK1; PK1; PRK1; EGVEGF; EG-VEGF

uniprot entry name :

PROK1_HUMAN

host :

E Coli

sequence length :

105

sequence :

The sequence of the first five N-terminal amino acids was determined and was found to be Ala-Val-Ile-Thr-Gly.

purity :

Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.

form :

The protein was lyophilized from a concentrated (1mg/ml) solution with no additives. Sterile Filtered White lyophilized (freeze-dried) powder.

storage stability :

Lyophilized EG-VEGF Human Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution EG-VEGF should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.Please prevent freeze-thaw cycles.

other info2 :

Solubility: It is recommended to reconstitute the lyophilized Endocrine Gland Vascular Endothelial Growth Factor in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

products categories :

CYTOKINES AND GROWTH FACTORS; Growth Factors; VEGF

products description :

Description: EG-VEGF Human Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 86 amino acids and having a molecular mass of 9605 Dalton.The EG-VEGF is purified by proprietary chromatographic techniques. Introduction: Endocrine gland-derived vascular endothelial growth factor (EG-VEGF) induces proliferation, migration, and fenestration in capillary endothelial cells derived from endocrine glands. Its expression is induced by hypoxia and is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta). Its expression is often complementary to the expression of VEGF (MIM 192240), suggesting that these molecules function in a coordinated manner. EG-VEGF potently contracts gastrointestinal (gi) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types.

ncbi gi num :

14165282

ncbi acc num :

NP_115790.1

ncbi gb acc num :

NM_032414.2

uniprot acc num :

P58294

ncbi mol weight :

11,715 Da

ncbi pathways :

Class A/1 (Rhodopsin-like Receptors) Pathway (106357); Defective ACTH Causes Obesity And Pro-opiomelanocortinin Deficiency (POMCD) Pathway (1127664); Disease Pathway (530764); G Alpha (q) Signalling Events Pathway (106043); GPCR Downstream Signaling Pathway (119548); GPCR Ligand Binding Pathway (161020); Gastrin-CREB Signalling Pathway Via PKC And MAPK (645295); Metabolic Disorders Of Biological Oxidation Enzymes Pathway (1127637); Peptide Ligand-binding Receptors Pathway (106358); Signal Transduction Pathway (477114)

ncbi summary :

The protein encoded by this gene induces proliferation, migration, and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. It has little or no effect on a variety of other endothelial and non-endothelial cell types. Its expression is restricted to the steroidogenic glands (ovary, testis, adrenal, and placenta), is induced by hypoxia, and often complementary to the expression of vascular endothelial growth factor (VEGF), suggesting that these molecules function in a coordinated manner. [provided by RefSeq, Sep 2011]

uniprot summary :

PROK1: Potently contracts gastrointestinal (GI) smooth muscle. Induces proliferation, migration and fenestration (the formation of membrane discontinuities) in capillary endothelial cells derived from endocrine glands. Has little or no effect on a variety of other endothelial and non-endothelial cell types. Induces proliferation and differentiation, but not migration, of enteric neural crest cells. Directly influences neuroblastoma progression by promoting the proliferation and migration of neuroblastoma cells. Positively regulates PTGS2 expression and prostaglandin synthesis. May play a role in placentation. May play a role in normal and pathological testis angiogenesis. Belongs to the AVIT (prokineticin) family. Protein type: Cell cycle regulation; Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 1p21. Cellular Component: extracellular region. Molecular Function: growth factor activity. Biological Process: activation of MAPK activity; positive regulation of cell division; positive regulation of cell proliferation; angiogenesis; regulation of angiogenesis

size1 :

0.005 mg

price1 :

140 USD

size2 :

0.02 mg

price2 :

205

size3 :

1 mg

price3 :

2665

more info or order :

MyBioSource product webpage