protein

Recombinant Human Omentin

MBS142178

0.002 mg

140 USD

Recombinant Protein

Recombinant Human Omentin

Omentin

Omentin Human; Omentin Human Recombinant; Intelectin-1; HL1; LFR; HL-1; INTL; ITLN; hIntL; Omentin

intelectin-1; Intelectin-1; intelectin-1; ITLN-1; endothelial lectin HL-1; galactofuranose-binding lectin; intestinal lactoferrin receptor; intelectin 1 (galactofuranose binding); Endothelial lectin HL-1; Galactofuranose-binding lectin; Intestinal lactoferrin receptor; Omentin

ITLN1; ITLN1; HL1; LFR; HL-1; INTL; ITLN; hIntL; omentin; INTL; ITLN; LFR; ITLN-1

ITLN1_HUMAN

E Coli

313

MNQLSFLLFL IATTRGWSTD EANTYFKEWTCSSSPSLPRS CKEIKDECPS AFDGLYFLRT ENGVIYQTFC DMTSGGGGWT LVASVHENDM RGKCTVGDRW SSQQGSKADY PEGDGNWANY NTFGSAEAAT SDDYKNPGYY DIQAKDLGIW HVPNKSPMQH WRNSSLLRYR TDTGFLQTLG HNLFGIYQKY PVKYGEGKCW TDNGPVIPVV YDFGDAQKTA SYYSPYGQRE FNNERAANAL CAGMRVTGCN TEHHCIGGGG YFPEASPQQC GDFSGFDWSG YGTHVGYSSS REITEAAVLLFYR.

Greater than 90.0% as determined by SDS-PAGE.

Each mg of lyophilized powder contains 20mM NaP, pH-7.5 and 0.5% manntiol. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Intelectin although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution Intelectin should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Omentin in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

CYTOKINES AND GROWTH FACTORS; Growth Factors; Omentin

Description: Omentin Human Recombinant is produced in E Coli by recombinant DNA technology is a single, polypeptide chain containing 313 amino acids and having a molecular mass of 35 kDa. Intelectin is purified by proprietary chromatographic techniques. Introduction: Omentin is a recently recognized gene highly localized to the mental tissue (visceral adipose tissue). Omentin is present in the stromal vascular cells in the adipose tissue rather than in the adipocytes. Omentin is predominantly expressed in the visceral adipose tissue than the subcutaneous tissue, with the omentin mRNA being 150 times higher in the visceral adipose tissue. Omentin has also been detected in human blood using western blot analysis, and seems to increase insulin-stimulated glucose uptake in 3T3-L1 adipocytes in mice. Omentin seems to increase Akt phosphorylation irrespective of insulin presence. Its role in glucose metabolism and obesity remains to be described; an insulin-sensitizing action is possible.Differences in Omentin expression has been noted in adipose tissue from normals and patients with inflammatory bowel disease although its significance is unknown.

31542986

NP_060095.2

NM_017625.2

Q8WWA0

34,962 Da

ITLN1: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. Protein type: Membrane protein, GPI anchor. Chromosomal Location of Human Ortholog: 1q21.3. Cellular Component: brush border membrane; receptor complex; lipid raft. Molecular Function: carbohydrate binding. Biological Process: positive regulation of glucose import; response to nematode; positive regulation of protein amino acid phosphorylation

0.002 mg

140 USD

0.01 mg

205

1 mg

5025