protein

Recombinant Rat Growth Hormone

MBS142173

0.1 mg

315 USD

Recombinant Protein

Recombinant Rat Growth Hormone

Growth Hormone

GH Rat; Growth Hormone Rat Recombinant; GH1; GH; GHN; GH-N; hGH-N; Pituitary growth hormone; Growth hormone 1; Somatotropin

somatotropin; Somatotropin; somatotropin; growth hormone 1; Growth hormone

rGH

Gh1; Gh1; Gh; RNGHGP; Gh

SOMA_RAT

E Coli

216

Greater than 97.0% as determined by: (a) Analysis by SEC-HPLC. (b) Analysis by SDS-PAGE.

The protein (1mg/ml) was lyophilized after extensive dialyses against 5mM phosphate buffer, 5mg mannitol and 1mg glycine. Sterile Filtered White lyophilized (freeze-dried) powder.

Lyophilized Growth Hormone Rat although stable at room temperature for 3 weeks, should be stored desiccated below -18 degree C. Upon reconstitution GH Rat should be stored at 4 degree C between 2-7 days and for future use below -18 degree C.For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Please prevent freeze-thaw cycles.

Solubility: It is recommended to reconstitute the lyophilized Growth Hormone Rat in sterile 18M Omega -cm H2O not less than 100 ug/ml, which can then be further diluted to other aqueous solutions.

CYTOKINES AND GROWTH FACTORS; Growth Factors; Growth Hormone

Description: Growth Hormone Rat Recombinant produced in E Coli is a single, non-glycosylated, polypeptide chain containing 190 amino acids and having a molecular mass of 21810 Dalton. GH is purified by proprietary chromatographic techniques. Introduction: GH is a member of the somatotropin/prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.

291463289

NP_001030020.2

NM_001034848.2

P01244

24,656 Da

Adipogenesis Pathway (198479); Cytokine Signaling In Immune System Pathway (1121619); Growth Hormone Receptor Signaling Pathway (1121636); Immune System Pathway (1121507); Jak-STAT Signaling Pathway (83469); Jak-STAT Signaling Pathway (488); Metabolism Of Proteins Pathway (1120813); Neuroactive Ligand-receptor Interaction Pathway (83445); Neuroactive Ligand-receptor Interaction Pathway (462); Nuclear Signaling By ERBB4 Pathway (1120687)

ligand for growth hormone receptor; plays a role in a number of signaling pathways [RGD, Feb 2006]

0.1 mg

315 USD

0.2 mg

400

1 mg

1220